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Spyre Therapeutics, Inc. Common Stock

SYRE Real Time Price USD
N/A
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Overview
Financials
Forecast
Insiders
Institutions
Compensation
Government
Ownership
News
Income
Balance Sheet
Cash Flow
Revenue Breakdown

Recent trades of SYRE by members of U.S. Congress

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No Congress Trading data for this ticker

Congress Trading Dashboard
SYRE Stock Insider Trading Activity Follow @QuiverQuant for major insider updates

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Closing Price
Purchase
Sale
Name
Type
Shares
Price
Shares Held
Date
Reported
SYRE Stock Institutional Owners
Investor
Shares
Change in Shares
Market Value
Date
Reported
SYRE Derivatives Institutional Owners
Investor
Type
Shares
Change in Shares
Market Value
Date
Reported

Recently reported changes in SYRE holdings by institutional investors

Quarterly net insider trading by SYRE's directors and management

* Insider trading data parsed from SEC Form 4 filings by Quiver Quantitative. Sign up for the Quiver API for real-time access.

About

Backtest Start Date
CAGR (Total)
Return (30d)
Return (1Y)
  • 1M
  • 3M
  • 6M
  • YTD
  • 1Y
  • 2Y
  • 5Y
  • MAX

About

Backtest Start Date

Key Metrics

Return (1d)

Return (30d)

Return (1Y)

CAGR (Total)

Max Drawdown

Beta

Alpha

Sharpe Ratio

Win Rate

Average Win

Average Loss

Annual Volatility

Annual Std Dev

Information Ratio

Treynor Ratio

Total Trades

Show More
Metrics Definitions

Disclaimer: The performance results shown are based on historical backtesting and are hypothetical in nature. Backtested performance does not represent actual trading and does not account for all market factors that may affect execution, such as liquidity, slippage, and changing market conditions. Past performance is not necessarily indicative of future results. There is no guarantee that any trading strategy will be profitable or avoid losses.

  • Alpha

    Measures a portfolio's risk-adjusted performance against that of its benchmark

    Learn More about Alpha
  • Annual Standard Deviation

    Measures how much the portfolio's total return varies from its mean or average.

    Learn More about Annual Standard Deviation
  • Annual Volatility

    A statistical measure of the dispersion of returns for the portfolio.

    Learn More about Annual Volatility
  • Average Win

    The average return (%) for trades that resulted in a positive return.

  • Average Loss

    The average return (%) for trades that resulted in a negative return.

  • Beta

    A measure of the volatility of the portfolio compared to the market as a whole.

    Learn More about Beta
  • CAGR

    CAGR (Compounded Annual Growth Rate), is the historical annualized rate of return for an investment strategy, throughout the backtest period.

    Learn More about CAGR
  • Information Ratio

    A measurement of portfolio returns beyond the returns of its benchmark compared to the volatility of those returns.

    Learn More about Information Ratio
  • Max Drawdown

    the maximum observed loss from a peak to a trough of a portfolio, before a new peak is attained.

    Learn More about Max Drawdown
  • Sharpe Ratio

    The Sharpe Ratio is a measure of historical risk-adjusted return, which quantifies the amount of return that an investor received per unit of risk.

    Learn More about Sharpe Ratio
  • Total Trades

    The total number of trades made by this strategy.

  • Treynor Ratio

    Attempts to measure how successful an investment is in providing compensation to investors for taking on investment risk.

    Learn More about Treynor Ratio
  • Win Rate

    The percentage of total trades that resulted in a positive return.

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Government lobbying spending instances

  • $10,000 Jul 17, 2026 Issue: Health Issues
  • $40,000 Apr 20, 2026 Issue: Health Issues
  • $10,000 Jan 15, 2026 Issue: Health Issues

Former government officials who have lobbied for SYRE

2 former government officials from 1 congressional office at 1 lobbying firm have lobbied for SYRE, most recently Apr 20, 2026.

  • Luke Albert House New Intern, Rep. Horn (2019) Formerly Horn · ARNOLD & PORTER KAYE SCHOLER LLP · Apr 20, 2026
  • Saxby Chambliss
    Bobby Mcmillin Senate New General Counsel, Senate Committee on Health, Education, Labor, & Pensions (HELP) (2015-2019); Counsel, Senate HELP Committee (2015); Counsel, Sen. Chambliss (2013-2015); Regional Rep., Sen. Chambliss (2012-13); Press Intern, Sen. Chambliss (2007) Formerly with Saxby Chambliss · ARNOLD & PORTER KAYE SCHOLER LLP · Nov 17, 2025

SYRE Estimated quarterly lobbying spending

SYRE Revenue by Segment or Geography

By Segment
By Geography
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No Revenue by Segment data for this ticker

Revenue Breakdown Dashboard
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No Revenue by Geography data for this ticker

Revenue Breakdown Dashboard
SYRE Income Statement
SYRE Balance Sheet
SYRE Cash Flow
U.S. Patents

New SYRE patent grants

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No new patents for this ticker

U.S. Patents Dashboard
Government Contracts

Federal grants, loans, and purchases

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No Government Contracts for this ticker

Government Contracts Dashboard
Government Contracts

Estimated quarterly amount awarded to SYRE from public contracts

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No recent Government Contracts for this ticker

Government Contracts Dashboard
SYRE News

Recent insights relating to SYRE

CNBC Recommendations

Recent picks made for SYRE stock on CNBC

Top ETF Holders

ETFs with the largest estimated holdings in SYRE

SYRE Analyst Ratings

SYRE Stock Forecasts
...

  • ... Highest Price Target
  • ... Median Price Target
  • ... Lowest Price Target
SYRE Analyst Forecasts
Analyst
Firm
Current
Previous
Date
Frequently Asked Questions
  • Is $SYRE stock a Buy, Sell, or Hold?

  • What is the price target for $SYRE stock?

* Analyst consensus is not financial advice. Please see our data disclaimers .

SYRE Top Shareholders
Shareholder
Shares Held
SYRE Options Owners
Shareholder
Security
Underlying Shares
Frequently Asked Questions
  • Who owns $SYRE stock?

  • Who owns the most shares of $SYRE stock?

  • What funds own $SYRE stock?

* These are estimates based on data taken from SEC filings. There may be inaccuracies due to parsing errors, accidental double-counting, incorrect classification of indirectly owned shares, or any other number of issues.

SYRE Stock Smart Score

The Quiver Smart Score combines our data on Congress Trading, Lobbying, Insider Trading, CNBC Mentions and more to provide a comprehensive view of the strength of a stock's underlying data.

The Smart Score grades stocks on a scale of 1 (weakest) to 10 (strongest) based on the strength of the underlying data.
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Score Breakdown
Bull Case vs Bear Case

See concise summaries of analyst reports, presenting both bullish and bearish arguments for a stock.

Example:

Bulls Say:

The Bulls Say summary highlights positive aspects of the stock.

Bears Say:

The Bears Say summary points out potential risks and negative aspects of the stock.

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About SYRE

Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

  • Address Waltham, MA
  • Market Cap 8.1 billion
  • Employees 112
  • Industrial Classification Pharmaceutical Preparations

Spyre Therapeutics, Inc. Common Stock (SYRE) Historical Stock Prices

Spyre Therapeutics, Inc. Common Stock (SYRE) closed at $91.97 on September 22, 2026. Over the past year its adjusted close ranged from $15.29 to $108.92. Daily prices go back to April 7, 2016, 2,630 trading days in all.

  • 1 month-13.64%
  • 3 months-5.23%
  • Year to date+180.74%
  • 1 year+501.50%
  • 3 years+675.46%
  • 5 years+1,083.66%
  • Max+841.35%
See every congressional and insider trade on the SYRE price chart

Quiver Premium charts SYRE's full daily history since 2014 with each congressional purchase and sale and every open-market insider purchase marked on the price line, with hover details for each trade.

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Last 12 months, newest first

Access Raw Data Daily prices since 2014 for every ticker, through the Quiver API
DateOpenHighLowCloseAdj. CloseVolume
Sep 22, 2026 91.53 93.58 89.90 91.97 91.97 1,223,437
Sep 21, 2026 91.07 94.06 89.65 92.03 92.03 1,448,750
Sep 18, 2026 92.82 93.34 89.85 90.25 90.25 3,357,066
Sep 17, 2026 92.86 95.19 91.14 92.68 92.68 1,438,926
Sep 16, 2026 91.38 93.06 90.48 91.17 91.17 1,257,641
Sep 15, 2026 90.82 91.07 88.47 90.95 90.95 858,487
Sep 14, 2026 90.21 91.40 89.43 90.80 90.80 1,101,160
Sep 11, 2026 90.00 91.41 87.89 90.60 90.60 886,055
Sep 10, 2026 85.56 88.72 85.26 88.71 88.71 902,458
Sep 9, 2026 88.07 89.57 86.85 86.93 86.93 1,005,796
Sep 8, 2026 85.00 92.10 85.00 90.79 90.79 1,249,656
Sep 4, 2026 86.45 89.18 84.68 88.98 88.98 803,857
Sep 3, 2026 86.71 87.90 85.78 87.25 87.25 1,054,194
Sep 2, 2026 88.05 90.18 84.00 87.05 87.05 1,361,712
Sep 1, 2026 87.06 90.00 85.00 88.50 88.50 1,429,114
Aug 31, 2026 89.15 90.97 86.40 89.33 89.33 1,913,157
Aug 28, 2026 91.75 93.39 89.45 90.36 90.36 1,266,563
Aug 27, 2026 93.61 94.94 91.25 93.61 93.61 1,165,484
Aug 26, 2026 92.41 96.22 90.60 93.61 93.61 3,115,250
Aug 25, 2026 109.02 110.15 106.94 107.36 107.36 923,599
Aug 24, 2026 106.49 108.02 104.94 106.65 106.65 640,581
Aug 21, 2026 108.85 110.00 105.71 106.49 106.49 1,014,917
Aug 20, 2026 106.60 108.18 104.56 107.79 107.79 700,636
Aug 19, 2026 110.00 110.17 104.17 108.92 108.92 1,166,126
Aug 18, 2026 102.46 108.62 101.44 107.82 107.82 949,560
Aug 17, 2026 102.94 104.96 102.26 104.60 104.60 891,634
Aug 14, 2026 101.21 104.13 95.61 103.63 103.63 559,504
Aug 13, 2026 101.00 103.84 100.90 101.85 101.85 525,434
Aug 12, 2026 105.06 105.06 99.00 104.09 104.09 909,634
Aug 11, 2026 105.33 105.44 99.84 102.74 102.74 931,734
Aug 10, 2026 106.19 107.00 103.33 105.33 105.33 822,714
Aug 7, 2026 106.01 106.67 103.64 104.91 104.91 526,596
Aug 6, 2026 102.39 106.75 101.64 103.42 103.42 454,482
Aug 5, 2026 104.94 108.14 100.88 104.35 104.35 1,037,497
Aug 4, 2026 98.27 105.25 97.03 104.94 104.94 831,997
Aug 3, 2026 97.15 99.58 92.71 94.93 94.93 898,396
Jul 31, 2026 100.58 100.58 95.27 98.33 98.33 621,726
Jul 30, 2026 98.26 101.88 97.39 101.50 101.50 851,502
Jul 29, 2026 99.38 100.98 94.52 97.87 97.87 1,216,609
Jul 28, 2026 97.19 100.93 92.37 99.96 99.96 1,513,005
Jul 27, 2026 102.01 105.05 98.87 100.04 100.04 669,885
Jul 24, 2026 100.56 103.57 98.79 102.13 102.13 812,829
Jul 23, 2026 97.06 100.35 97.00 99.99 99.99 635,067
Jul 22, 2026 102.39 102.39 99.06 99.17 99.17 596,165
Jul 21, 2026 99.07 103.31 98.50 102.70 102.70 776,544
Jul 20, 2026 101.02 102.92 97.28 97.33 97.33 750,187
Jul 17, 2026 94.26 101.36 92.37 100.23 100.23 1,091,487
Jul 16, 2026 103.32 103.32 93.37 94.12 94.12 1,370,654
Jul 15, 2026 100.21 102.58 95.14 102.07 102.07 1,520,637
Jul 14, 2026 96.06 105.09 94.95 98.95 98.95 2,776,366
Jul 13, 2026 95.72 96.81 92.67 93.73 93.73 1,038,857
Jul 10, 2026 98.75 99.34 94.13 97.74 97.74 779,183
Jul 9, 2026 96.36 99.00 96.11 98.75 98.75 1,329,833
Jul 8, 2026 94.36 95.59 90.64 95.40 95.40 1,240,474
Jul 7, 2026 90.00 95.16 86.60 94.23 94.23 1,305,918
Jul 6, 2026 87.27 91.89 86.61 88.74 88.74 1,388,917
Jul 2, 2026 89.11 89.69 85.17 86.63 86.63 973,964
Jul 1, 2026 88.21 89.02 86.41 88.89 88.89 1,682,238
Jun 30, 2026 90.30 91.95 88.60 88.78 88.78 1,467,502
Jun 29, 2026 86.56 90.90 84.81 90.16 90.16 2,014,816
Jun 26, 2026 91.00 91.00 85.97 87.89 87.89 4,441,241
Jun 25, 2026 86.46 89.67 84.96 88.67 88.67 2,109,266
Jun 24, 2026 83.22 88.15 81.65 86.24 86.24 4,044,708
Jun 23, 2026 97.72 102.06 95.31 97.05 97.05 2,640,323
Jun 22, 2026 95.00 101.70 95.00 100.32 100.32 2,805,256
Jun 18, 2026 89.55 90.99 86.18 88.34 88.34 2,420,429
Jun 17, 2026 84.97 88.03 83.17 87.49 87.49 1,537,189
Jun 16, 2026 83.54 84.92 81.70 83.41 83.41 1,337,113
Jun 15, 2026 81.57 84.69 80.79 83.58 83.58 1,156,436
Jun 12, 2026 81.09 84.43 80.72 80.79 80.79 958,742
Jun 11, 2026 75.74 81.62 75.35 80.77 80.77 1,268,039
Jun 10, 2026 77.18 79.52 74.79 75.08 75.08 981,531
Jun 9, 2026 73.65 77.11 70.89 76.44 76.44 1,593,140
Jun 8, 2026 75.53 76.31 71.11 72.00 72.00 1,036,035
Jun 5, 2026 77.77 78.90 73.06 73.65 73.65 1,479,793
Jun 4, 2026 73.57 79.54 73.29 78.48 78.48 1,119,156
Jun 3, 2026 70.33 76.11 69.81 73.52 73.52 1,679,680
Jun 2, 2026 69.99 70.50 68.50 69.16 69.16 814,719
Jun 1, 2026 72.39 73.21 68.85 70.54 70.54 921,839
May 29, 2026 72.11 74.36 71.51 73.50 73.50 1,113,790
May 28, 2026 72.36 73.33 71.08 72.11 72.11 428,977
May 27, 2026 73.99 74.35 72.24 72.51 72.51 557,989
May 26, 2026 74.87 76.12 72.11 73.65 73.65 478,892
May 22, 2026 75.34 75.63 73.11 74.05 74.05 574,924
May 21, 2026 70.89 74.43 70.18 74.32 74.32 738,568
May 20, 2026 68.64 72.47 67.88 71.92 71.92 1,088,338
May 19, 2026 70.08 70.08 64.67 66.62 66.62 1,385,703
May 18, 2026 75.08 75.65 69.01 70.08 70.08 1,079,527
May 15, 2026 77.08 77.08 72.54 74.92 74.92 1,958,723
May 14, 2026 76.51 77.76 74.49 75.65 75.65 449,788
May 13, 2026 75.69 78.00 73.48 76.31 76.31 776,749
May 12, 2026 77.00 77.20 73.22 75.04 75.04 1,760,552
May 11, 2026 75.15 78.80 74.39 76.43 76.43 1,333,266
May 8, 2026 73.10 75.91 72.40 75.05 75.05 840,632
May 7, 2026 73.58 74.51 71.13 73.10 73.10 923,853
May 6, 2026 70.68 73.51 70.11 73.00 73.00 711,501
May 5, 2026 70.64 73.22 70.21 71.01 71.01 2,010,985
May 4, 2026 68.26 71.67 67.18 69.13 69.13 1,008,977
May 1, 2026 74.09 76.00 69.17 69.42 69.42 1,463,723
Apr 30, 2026 72.33 75.00 72.08 74.45 74.45 1,044,357
Apr 29, 2026 68.25 73.61 67.50 71.89 71.89 1,808,270
Apr 28, 2026 72.10 73.95 68.20 68.63 68.63 1,070,634
Apr 27, 2026 69.53 72.30 69.53 71.90 71.90 687,130
Apr 24, 2026 69.83 72.07 68.43 69.67 69.67 601,276
Apr 23, 2026 73.01 73.73 68.33 69.24 69.24 693,335
Apr 22, 2026 72.96 74.35 71.71 73.00 73.00 1,070,825
Apr 21, 2026 73.39 74.84 69.95 71.27 71.27 1,354,765
Apr 20, 2026 72.20 74.68 72.03 73.39 73.39 915,910
Apr 17, 2026 70.32 74.60 70.21 73.01 73.01 2,126,535
Apr 16, 2026 68.94 70.30 66.88 69.70 69.70 2,195,106
Apr 15, 2026 67.75 69.45 64.60 68.99 68.99 4,196,651
Apr 14, 2026 67.68 67.68 60.75 64.01 64.01 1,672,992
Apr 13, 2026 67.00 75.00 59.02 63.27 63.27 5,361,081
Apr 10, 2026 51.40 52.98 50.85 51.29 51.29 499,346
Apr 9, 2026 51.63 52.77 51.20 51.77 51.77 587,537
Apr 8, 2026 52.70 54.39 50.39 51.98 51.98 1,043,909
Apr 7, 2026 48.97 51.26 48.83 51.20 51.20 799,899
Apr 6, 2026 47.58 49.85 46.79 48.98 48.98 791,810
Apr 2, 2026 47.17 48.40 46.27 47.58 47.58 438,074
Apr 1, 2026 50.33 51.00 48.64 48.90 48.90 890,688
Mar 31, 2026 46.28 51.06 46.28 50.44 50.44 1,043,724
Mar 30, 2026 47.75 48.47 44.80 45.42 45.42 712,640
Mar 27, 2026 46.93 47.95 46.70 47.31 47.31 832,291
Mar 26, 2026 45.39 49.30 45.23 47.52 47.52 1,332,527
Mar 25, 2026 42.93 45.79 42.68 45.68 45.68 667,978
Mar 24, 2026 41.78 42.76 40.91 42.22 42.22 724,608
Mar 23, 2026 42.02 44.08 41.73 42.76 42.76 779,447
Mar 20, 2026 42.11 43.22 41.16 41.25 41.25 1,410,504
Mar 19, 2026 42.98 43.22 41.74 42.31 42.31 628,435
Mar 18, 2026 44.28 44.28 42.36 43.06 43.06 798,510
Mar 17, 2026 44.25 45.39 43.77 43.95 43.95 844,146
Mar 16, 2026 40.73 44.49 40.73 44.07 44.07 1,246,086
Mar 13, 2026 40.92 42.40 39.00 39.89 39.89 844,900
Mar 12, 2026 40.22 40.75 39.20 40.41 40.41 711,426
Mar 11, 2026 41.25 42.61 41.05 41.50 41.50 571,272
Mar 10, 2026 41.09 42.93 41.09 41.57 41.57 650,850
Mar 9, 2026 39.75 41.88 39.21 41.07 41.07 890,333
Mar 6, 2026 39.99 40.59 38.36 40.15 40.15 567,557
Mar 5, 2026 40.34 41.50 39.90 40.59 40.59 638,555
Mar 4, 2026 40.14 42.58 40.07 41.00 41.00 725,321
Mar 3, 2026 40.99 41.85 39.98 40.07 40.07 921,765
Mar 2, 2026 41.27 42.93 40.74 42.49 42.49 742,285
Feb 27, 2026 42.42 43.80 42.27 43.01 43.01 695,216
Feb 26, 2026 43.79 44.26 42.03 43.15 43.15 534,837
Feb 25, 2026 44.18 44.88 43.43 43.88 43.88 521,817
Feb 24, 2026 44.17 44.81 43.05 43.45 43.45 636,486
Feb 23, 2026 43.01 45.76 42.26 44.18 44.18 1,095,771
Feb 20, 2026 37.82 43.56 37.81 43.21 43.21 2,278,488
Feb 19, 2026 36.66 38.16 35.93 37.81 37.81 804,010
Feb 18, 2026 36.05 37.66 35.93 36.60 36.60 702,341
Feb 17, 2026 36.39 37.22 34.96 35.95 35.95 681,084
Feb 13, 2026 35.02 37.98 35.02 36.63 36.63 1,320,217
Feb 12, 2026 33.98 34.92 33.59 34.84 34.84 623,239
Feb 11, 2026 33.59 34.13 32.35 33.92 33.92 362,046
Feb 10, 2026 34.28 34.93 33.19 33.56 33.56 648,450
Feb 9, 2026 35.12 35.58 33.78 33.96 33.96 679,581
Feb 6, 2026 33.77 35.21 33.16 35.12 35.12 790,548
Feb 5, 2026 31.85 33.67 31.40 32.94 32.94 972,914
Feb 4, 2026 33.57 34.07 30.92 32.07 32.07 408,689
Feb 3, 2026 32.77 33.96 32.66 33.29 33.29 453,778
Feb 2, 2026 31.76 33.35 30.99 32.75 32.75 442,966
Jan 30, 2026 33.27 33.65 31.60 31.98 31.98 535,775
Jan 29, 2026 32.96 33.77 32.83 33.58 33.58 570,998
Jan 28, 2026 33.45 34.03 32.49 33.14 33.14 318,653
Jan 27, 2026 32.31 33.77 32.31 33.36 33.36 360,101
Jan 26, 2026 31.52 33.08 31.52 32.29 32.29 410,667
Jan 23, 2026 33.05 34.47 31.77 32.03 32.03 407,767
Jan 22, 2026 33.87 35.06 33.82 34.09 34.09 847,479
Jan 21, 2026 33.68 34.51 33.33 33.99 33.99 512,300
Jan 20, 2026 32.34 33.91 31.62 33.73 33.73 597,035
Jan 16, 2026 33.20 34.00 32.40 33.24 33.24 439,333
Jan 15, 2026 33.26 34.17 32.57 33.09 33.09 812,317
Jan 14, 2026 31.53 34.21 31.53 33.16 33.16 1,037,349
Jan 13, 2026 32.95 33.70 31.03 31.53 31.53 657,009
Jan 12, 2026 30.60 33.10 30.00 32.80 32.80 581,598
Jan 9, 2026 30.46 31.45 30.36 30.61 30.61 456,078
Jan 8, 2026 30.42 30.70 29.60 30.14 30.14 569,338
Jan 7, 2026 30.45 31.69 30.21 31.05 31.05 588,705
Jan 6, 2026 29.92 30.39 29.43 30.33 30.33 752,785
Jan 5, 2026 30.49 30.55 28.00 29.96 29.96 987,156
Jan 2, 2026 32.76 33.31 30.11 30.58 30.58 888,699
Dec 31, 2025 31.78 32.84 31.52 32.76 32.76 533,201
Dec 30, 2025 32.45 32.53 31.50 31.88 31.88 392,912
Dec 29, 2025 32.77 33.22 32.05 32.56 32.56 348,455
Dec 26, 2025 33.00 33.02 32.30 32.94 32.94 307,908
Dec 24, 2025 33.38 34.10 32.79 33.05 33.05 291,964
Dec 23, 2025 33.84 34.44 32.96 33.23 33.23 518,431
Dec 22, 2025 32.93 34.52 32.50 34.20 34.20 1,181,057
Dec 19, 2025 33.82 34.84 33.22 33.40 33.40 4,010,057
Dec 18, 2025 33.66 34.24 32.88 33.47 33.47 642,203
Dec 17, 2025 33.51 34.32 32.76 33.06 33.06 493,471
Dec 16, 2025 33.00 33.52 32.26 32.97 32.97 519,821
Dec 15, 2025 33.93 34.96 33.15 33.34 33.34 729,374
Dec 12, 2025 34.36 35.17 33.24 33.62 33.62 731,900
Dec 11, 2025 34.77 35.31 34.17 34.36 34.36 666,850
Dec 10, 2025 33.70 34.94 33.51 34.66 34.66 765,699
Dec 9, 2025 34.48 34.98 33.52 33.68 33.68 1,123,796
Dec 8, 2025 33.95 34.96 33.45 34.63 34.63 1,178,780
Dec 5, 2025 33.56 34.06 33.00 33.45 33.45 553,532
Dec 4, 2025 32.18 34.54 31.44 33.51 33.51 938,173
Dec 3, 2025 28.85 32.26 28.50 32.20 32.20 1,314,287
Dec 2, 2025 28.85 29.84 28.16 28.40 28.40 643,630
Dec 1, 2025 30.55 30.55 28.45 28.66 28.66 867,260
Nov 28, 2025 30.00 30.21 29.75 30.00 30.00 562,693
Nov 26, 2025 29.21 29.78 28.71 29.75 29.75 503,212
Nov 25, 2025 26.73 29.50 26.64 29.20 29.20 630,512
Nov 24, 2025 24.95 27.21 24.58 26.97 26.97 962,564
Nov 21, 2025 23.29 24.97 23.01 24.26 24.26 496,266
Nov 20, 2025 24.77 25.42 23.22 23.47 23.47 627,741
Nov 19, 2025 24.52 25.07 23.69 24.30 24.30 586,745
Nov 18, 2025 24.18 24.70 23.75 24.10 24.10 493,692
Nov 17, 2025 23.47 25.02 23.03 24.36 24.36 724,273
Nov 14, 2025 22.26 24.50 22.13 23.50 23.50 543,588
Nov 13, 2025 23.13 23.57 22.47 22.63 22.63 514,561
Nov 12, 2025 23.39 24.19 22.91 23.43 23.43 611,385
Nov 11, 2025 22.21 23.68 21.63 23.35 23.35 533,917
Nov 10, 2025 22.93 23.00 21.96 22.18 22.18 416,578
Nov 7, 2025 21.88 22.54 21.14 22.52 22.52 569,245
Nov 6, 2025 22.53 22.98 21.88 22.39 22.39 504,733
Nov 5, 2025 23.37 23.50 22.03 22.85 22.85 813,174
Nov 4, 2025 23.29 23.56 22.87 22.98 22.98 696,263
Nov 3, 2025 23.95 24.45 22.42 23.78 23.78 1,045,776
Oct 31, 2025 24.10 24.59 23.65 24.46 24.46 683,321
Oct 30, 2025 23.79 24.68 23.78 24.26 24.26 488,413
Oct 29, 2025 24.48 25.00 23.52 23.83 23.83 1,078,012
Oct 28, 2025 24.30 25.05 24.29 24.64 24.64 751,103
Oct 27, 2025 24.01 25.00 23.65 24.57 24.57 1,270,011
Oct 24, 2025 22.56 23.59 22.35 23.37 23.37 700,704
Oct 23, 2025 22.19 22.89 21.90 22.37 22.37 675,338
Oct 22, 2025 23.11 23.40 21.88 22.21 22.21 906,704
Oct 21, 2025 23.50 24.02 22.84 23.25 23.25 1,037,533
Oct 20, 2025 22.86 23.53 22.23 23.49 23.49 995,917
Oct 17, 2025 21.93 22.98 21.90 22.47 22.47 1,680,041
Oct 16, 2025 22.04 23.49 21.82 22.24 22.24 2,427,034
Oct 15, 2025 21.60 22.30 21.01 22.19 22.19 2,528,127
Oct 14, 2025 18.91 21.61 18.71 21.00 21.00 5,559,701
Oct 13, 2025 19.15 19.71 18.12 18.91 18.91 647,456
Oct 10, 2025 21.02 21.29 19.03 19.14 19.14 1,200,304
Oct 9, 2025 17.66 21.51 17.65 21.17 21.17 2,800,140
Oct 8, 2025 16.07 17.90 16.04 17.68 17.68 1,144,896
Oct 7, 2025 16.68 16.79 16.00 16.02 16.02 439,743
Oct 6, 2025 16.03 16.71 15.86 16.67 16.67 654,915
Oct 3, 2025 16.17 16.30 15.88 15.89 15.89 430,489
Oct 2, 2025 16.51 16.70 15.87 15.98 15.98 290,478
Oct 1, 2025 16.73 17.19 16.37 16.46 16.46 555,439
Sep 30, 2025 16.33 16.79 15.81 16.76 16.76 550,934
Sep 29, 2025 16.27 16.42 15.49 16.36 16.36 965,629
Sep 26, 2025 16.05 16.73 15.70 16.24 16.24 985,408
Sep 25, 2025 16.87 17.00 15.56 15.61 15.61 1,057,706
Sep 24, 2025 15.91 17.12 15.80 17.00 17.00 753,106
Sep 23, 2025 15.22 16.05 15.11 16.02 16.02 943,941
Sep 22, 2025 14.86 15.45 14.51 15.29 15.29 608,142

Open, high, low and close are the prices as traded. Adjusted close accounts for splits and dividends, and is what the chart and returns use. Where a company changed its ticker, its history under the old symbol is included.

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Spyre Therapeutics, Inc. Common Stock Executive Compensation

We estimate that -- received a compensation of -- in --, making them the highest paid executive at SYRE, per a recent SEC DEF 14A filing.



Name
Role
Salary
Bonus
Stock/Option Awards
Total Compensation