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Karyopharm Therapeutics Inc.

KPTI Real Time Price USD
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Overview
Financials
Forecast
Insiders
Institutions
Compensation
Government
Ownership
News
Income
Balance Sheet
Cash Flow
Revenue Breakdown

Recent trades of KPTI by members of U.S. Congress

KPTI Stock Insider Trading Activity Follow @QuiverQuant for major insider updates

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Closing Price
Purchase
Sale
Name
Type
Shares
Price
Shares Held
Date
Reported
KPTI Stock Institutional Owners
Investor
Shares
Change in Shares
Market Value
Date
Reported
KPTI Derivatives Institutional Owners
Investor
Type
Shares
Change in Shares
Market Value
Date
Reported

Recently reported changes in KPTI holdings by institutional investors

Quarterly net insider trading by KPTI's directors and management

* Insider trading data parsed from SEC Form 4 filings by Quiver Quantitative. Sign up for the Quiver API for real-time access.

About

Backtest Start Date
CAGR (Total)
Return (30d)
Return (1Y)
  • 1M
  • 3M
  • 6M
  • YTD
  • 1Y
  • 2Y
  • 5Y
  • MAX

About

Backtest Start Date

Key Metrics

Return (1d)

Return (30d)

Return (1Y)

CAGR (Total)

Max Drawdown

Beta

Alpha

Sharpe Ratio

Win Rate

Average Win

Average Loss

Annual Volatility

Annual Std Dev

Information Ratio

Treynor Ratio

Total Trades

Show More
Metrics Definitions

Disclaimer: The performance results shown are based on historical backtesting and are hypothetical in nature. Backtested performance does not represent actual trading and does not account for all market factors that may affect execution, such as liquidity, slippage, and changing market conditions. Past performance is not necessarily indicative of future results. There is no guarantee that any trading strategy will be profitable or avoid losses.

  • Alpha

    Measures a portfolio's risk-adjusted performance against that of its benchmark

    Learn More about Alpha
  • Annual Standard Deviation

    Measures how much the portfolio's total return varies from its mean or average.

    Learn More about Annual Standard Deviation
  • Annual Volatility

    A statistical measure of the dispersion of returns for the portfolio.

    Learn More about Annual Volatility
  • Average Win

    The average return (%) for trades that resulted in a positive return.

  • Average Loss

    The average return (%) for trades that resulted in a negative return.

  • Beta

    A measure of the volatility of the portfolio compared to the market as a whole.

    Learn More about Beta
  • CAGR

    CAGR (Compounded Annual Growth Rate), is the historical annualized rate of return for an investment strategy, throughout the backtest period.

    Learn More about CAGR
  • Information Ratio

    A measurement of portfolio returns beyond the returns of its benchmark compared to the volatility of those returns.

    Learn More about Information Ratio
  • Max Drawdown

    the maximum observed loss from a peak to a trough of a portfolio, before a new peak is attained.

    Learn More about Max Drawdown
  • Sharpe Ratio

    The Sharpe Ratio is a measure of historical risk-adjusted return, which quantifies the amount of return that an investor received per unit of risk.

    Learn More about Sharpe Ratio
  • Total Trades

    The total number of trades made by this strategy.

  • Treynor Ratio

    Attempts to measure how successful an investment is in providing compensation to investors for taking on investment risk.

    Learn More about Treynor Ratio
  • Win Rate

    The percentage of total trades that resulted in a positive return.

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Government lobbying spending instances

  • $100,000 Jan 20, 2026 Issue: Health Issues
  • $40,000 Jan 21, 2020 Issue: Pharmacy
  • $60,000 Oct 21, 2019 Issue: Pharmacy
  • $60,000 Jul 22, 2019 Issue: Pharmacy
  • $60,000 Apr 22, 2019 Issue: Pharmacy
  • $60,000 Jan 23, 2019 Issue: Pharmacy

Former government officials who have lobbied for KPTI

8 former government officials from 4 congressional offices at 2 lobbying firms have lobbied for KPTI, most recently Jul 20, 2026.

  • Orrin G. Hatch
    Patricia Deloatche Senate Health Policy Director, Sen Orrin Hatch; Chief of Staff, Legislative Director, Legislative Assistant, Rep. Mike Bilirakis Formerly with Orrin G. Hatch · SIDLEY AUSTIN LLP · Jul 20, 2026
  • Abigail Carroll House Detailee to the Energy and Commerce Committee, U.S House of Representatives Formerly Detailee to the Energy and Commerce Committee, U.S House of Representatives · SIDLEY AUSTIN LLP · Jul 20, 2026
  • Brent Del Monte Other See prior filing Formerly See prior filing · BGR GOVERNMENT AFFAIRS · Jan 21, 2020
  • John Stone Other See prior filing Formerly See prior filing · BGR GOVERNMENT AFFAIRS · Jan 21, 2020
  • Matt Hoffmann Other See prior filing Formerly See prior filing · BGR GOVERNMENT AFFAIRS · Jan 21, 2020
  • Robb Walton Other See prior filing Formerly See prior filing · BGR GOVERNMENT AFFAIRS · Jan 21, 2020
  • Remy Mason Other See prior filing Formerly See prior filing · BGR GOVERNMENT AFFAIRS · Jan 21, 2020
  • David Boyer Other See prior filing Formerly See prior filing · BGR GOVERNMENT AFFAIRS · Jul 22, 2019

KPTI Estimated quarterly lobbying spending

KPTI Revenue by Segment or Geography

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Revenue Breakdown Dashboard
KPTI Income Statement
KPTI Balance Sheet
KPTI Cash Flow
U.S. Patents

New KPTI patent grants

  • Patent Title: Crystalline form of selinexor Aug. 18, 2026
  • Patent Title: Methods of synthesis of heteroaryl derivatives of triazolyl acrylamides and crystalline forms Jul. 07, 2026
  • Patent Title: Nuclear transport modulators and uses thereof Mar. 17, 2026
  • Patent Title: Co-crystal forms of selinexor Feb. 24, 2026
  • Patent Title: Process for preparing xpo1 inhibitors and intermediates for use in the preparation of xpo1 inhibitors Nov. 25, 2025
  • Patent Title: Polymorphs of selinexor Jul. 29, 2025
  • Patent Title: Substituted benzofuranyl and benzoxazolyl compounds and uses thereof Jun. 17, 2025
  • Patent Title: Combination of xpo1 inhibitors and second agents for the treatment of prostate cancer Jun. 03, 2025
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof May. 06, 2025
  • Patent Title: Nuclear transport modulators and uses thereof Apr. 02, 2024
  • Patent Title: Polymorphs of selinexor Nov. 07, 2023
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Oct. 17, 2023
  • Patent Title: Polymorphs of selinexor Sep. 12, 2023
  • Patent Title: Polymorphs of selinexor Sep. 05, 2023
  • Patent Title: Nuclear transport modulators and uses thereof Sep. 21, 2021
  • Patent Title: Polymorphs of selinexor Aug. 03, 2021
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Jun. 15, 2021
  • Patent Title: Substituted benzofuranyl and benzoxazolyl compounds and uses thereof May. 18, 2021
  • Patent Title: Multicyclic compounds and uses thereof Dec. 08, 2020
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Jan. 28, 2020
  • Patent Title: Nuclear transport modulators and uses thereof Jan. 07, 2020
  • Patent Title: Polymorphs of selinexor Dec. 31, 2019
  • Patent Title: Nuclear transport modulators and uses thereof Sep. 10, 2019
  • Patent Title: Substituted benzofuranyl and benzoxazolyl compounds and uses thereof Sep. 03, 2019
  • Patent Title: (s,e)-3-(6-aminopyridin-3-yl)-n-((5-(4-(3-fluoro-3-methylpyrrolidine-1-carbonyl)phenyl-7-(4-fluorophenyl)benzofuran-2-yl)methyl)acrylamide for the treatment of cancer Jul. 30, 2019
  • Patent Title: Methods of promoting wound healing using crm1 inhibitors Feb. 12, 2019
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Jan. 08, 2019
  • Patent Title: Multicyclic compounds and methods of using same Jun. 12, 2018
  • Patent Title: Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof Apr. 10, 2018
  • Patent Title: Nuclear transport modulators and uses thereof Jan. 09, 2018
  • Patent Title: Substituted benzofuranyl and benzoxazolyl compounds and uses thereof Jan. 02, 2018
  • Patent Title: Nuclear transport modulators and uses thereof Aug. 22, 2017
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Jul. 25, 2017
  • Patent Title: Nuclear transport modulators and uses thereof Mar. 07, 2017
  • Patent Title: Nuclear transport modulators and uses thereof Jan. 24, 2017
  • Patent Title: Nuclear transport modulators and uses thereof Aug. 30, 2016
  • Patent Title: Olefin containing nuclear transport modulators and uses thereof Apr. 05, 2016
  • Patent Title: Nuclear transport modulators and uses thereof Feb. 23, 2016
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Dec. 08, 2015
  • Patent Title: Nuclear transport modulators and uses thereof Aug. 04, 2015
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Jul. 14, 2015
  • Patent Title: Hydrazide containing nuclear transport modulators and uses thereof Apr. 07, 2015
  • Patent Title: Nuclear transport modulators and uses thereof Aug. 20, 2013
Government Contracts

Federal grants, loans, and purchases

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No Government Contracts for this ticker

Government Contracts Dashboard
Government Contracts

Estimated quarterly amount awarded to KPTI from public contracts

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No recent Government Contracts for this ticker

Government Contracts Dashboard
KPTI News

Recent insights relating to KPTI

CNBC Recommendations

Recent picks made for KPTI stock on CNBC

Top ETF Holders

ETFs with the largest estimated holdings in KPTI

KPTI Analyst Ratings

KPTI Stock Forecasts
...

  • ... Highest Price Target
  • ... Median Price Target
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KPTI Analyst Forecasts
Analyst
Firm
Current
Previous
Date
Frequently Asked Questions
  • Is $KPTI stock a Buy, Sell, or Hold?

  • What is the price target for $KPTI stock?

* Analyst consensus is not financial advice. Please see our data disclaimers .

KPTI Top Shareholders
Shareholder
Shares Held
KPTI Options Owners
Shareholder
Security
Underlying Shares
Frequently Asked Questions
  • Who owns $KPTI stock?

  • Who owns the most shares of $KPTI stock?

  • What funds own $KPTI stock?

* These are estimates based on data taken from SEC filings. There may be inaccuracies due to parsing errors, accidental double-counting, incorrect classification of indirectly owned shares, or any other number of issues.

KPTI Stock Smart Score

The Quiver Smart Score combines our data on Congress Trading, Lobbying, Insider Trading, CNBC Mentions and more to provide a comprehensive view of the strength of a stock's underlying data.

The Smart Score grades stocks on a scale of 1 (weakest) to 10 (strongest) based on the strength of the underlying data.
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Score Breakdown
Bull Case vs Bear Case

See concise summaries of analyst reports, presenting both bullish and bearish arguments for a stock.

Example:

Bulls Say:

The Bulls Say summary highlights positive aspects of the stock.

Bears Say:

The Bears Say summary points out potential risks and negative aspects of the stock.

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About KPTI

Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).

  • Address Newton, MA
  • Market Cap 41.3 million
  • Employees 228
  • Industrial Classification Pharmaceutical Preparations

Karyopharm Therapeutics Inc. (KPTI) Historical Stock Prices

Karyopharm Therapeutics Inc. (KPTI) closed at $1.82 on September 22, 2026. Over the past year its adjusted close ranged from $1.54 to $10.67. Daily prices go back to January 2, 2014, 3,199 trading days in all.

  • 1 month-7.14%
  • 3 months-81.14%
  • Year to date-75.27%
  • 1 year-68.89%
  • 3 years-89.45%
  • 5 years-98.08%
  • Max-99.47%
See every congressional and insider trade on the KPTI price chart

Quiver Premium charts KPTI's full daily history since 2014 with each congressional purchase and sale and every open-market insider purchase marked on the price line, with hover details for each trade.

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Last 12 months, newest first

Access Raw Data Daily prices since 2014 for every ticker, through the Quiver API
DateOpenHighLowCloseAdj. CloseVolume
Sep 22, 2026 1.87 1.92 1.78 1.82 1.82 986,900
Sep 21, 2026 1.85 1.93 1.78 1.86 1.86 1,624,741
Sep 18, 2026 1.77 1.89 1.67 1.88 1.88 1,901,077
Sep 17, 2026 1.75 1.85 1.66 1.79 1.79 1,089,114
Sep 16, 2026 1.54 1.72 1.54 1.70 1.70 1,353,909
Sep 15, 2026 1.59 1.70 1.52 1.54 1.54 1,329,482
Sep 14, 2026 1.55 1.62 1.55 1.60 1.60 991,814
Sep 11, 2026 1.50 1.61 1.24 1.61 1.61 6,737,667
Sep 10, 2026 1.68 1.68 1.59 1.62 1.62 800,950
Sep 9, 2026 1.72 1.75 1.65 1.69 1.69 772,567
Sep 8, 2026 1.77 1.79 1.70 1.72 1.72 1,007,320
Sep 4, 2026 1.77 1.84 1.75 1.79 1.79 577,786
Sep 3, 2026 1.79 1.81 1.72 1.77 1.77 819,676
Sep 2, 2026 1.90 1.94 1.73 1.79 1.79 1,296,285
Sep 1, 2026 2.02 2.06 1.84 1.85 1.85 1,598,051
Aug 31, 2026 1.91 2.14 1.79 2.06 2.06 2,028,979
Aug 28, 2026 1.98 1.99 1.86 1.87 1.87 827,353
Aug 27, 2026 1.99 2.06 1.93 1.94 1.94 1,108,229
Aug 26, 2026 1.92 1.99 1.86 1.96 1.96 753,814
Aug 25, 2026 1.87 1.95 1.87 1.92 1.92 1,060,619
Aug 24, 2026 1.95 1.96 1.83 1.86 1.86 845,772
Aug 21, 2026 1.85 1.97 1.82 1.96 1.96 876,794
Aug 20, 2026 2.00 2.00 1.82 1.82 1.82 865,646
Aug 19, 2026 1.93 2.02 1.93 2.00 2.00 792,127
Aug 18, 2026 1.88 1.96 1.82 1.93 1.93 1,145,247
Aug 17, 2026 2.02 2.03 1.79 1.81 1.81 1,387,590
Aug 14, 2026 1.97 2.06 1.97 2.02 2.02 886,922
Aug 13, 2026 2.03 2.09 1.92 1.99 1.99 1,727,137
Aug 12, 2026 2.10 2.15 2.00 2.03 2.03 1,836,839
Aug 11, 2026 1.93 2.18 1.93 2.10 2.10 1,962,554
Aug 10, 2026 2.14 2.18 1.92 1.96 1.96 1,795,726
Aug 7, 2026 1.96 2.12 1.91 2.12 2.12 1,792,750
Aug 6, 2026 1.88 2.00 1.88 1.95 1.95 1,189,123
Aug 5, 2026 1.94 2.06 1.88 1.91 1.91 2,376,615
Aug 4, 2026 2.00 2.11 1.94 1.96 1.96 3,792,123
Aug 3, 2026 1.94 2.05 1.80 1.97 1.97 4,514,606
Jul 31, 2026 2.19 2.43 1.80 1.92 1.92 22,398,319
Jul 30, 2026 6.98 7.09 6.55 7.01 7.01 4,540,851
Jul 29, 2026 7.04 7.47 6.73 6.86 6.86 436,891
Jul 28, 2026 7.10 7.14 6.75 7.09 7.09 531,286
Jul 27, 2026 7.45 7.84 7.01 7.09 7.09 527,473
Jul 24, 2026 7.15 7.61 6.99 7.41 7.41 900,248
Jul 23, 2026 7.14 7.19 6.75 7.09 7.09 680,130
Jul 22, 2026 7.92 8.02 7.05 7.18 7.18 713,636
Jul 21, 2026 7.49 8.27 7.46 7.87 7.87 943,081
Jul 20, 2026 9.40 9.45 6.49 7.47 7.47 2,330,172
Jul 17, 2026 9.35 9.59 9.31 9.51 9.51 205,243
Jul 16, 2026 9.55 9.84 9.36 9.38 9.38 236,381
Jul 15, 2026 9.85 9.86 9.38 9.53 9.53 316,488
Jul 14, 2026 10.07 10.17 9.82 10.01 10.01 481,544
Jul 13, 2026 10.19 10.30 9.71 10.05 10.05 431,397
Jul 10, 2026 10.30 10.59 9.88 10.34 10.34 320,246
Jul 9, 2026 10.76 10.76 10.09 10.20 10.20 281,109
Jul 8, 2026 10.02 10.86 9.91 10.67 10.67 737,365
Jul 7, 2026 9.58 10.05 9.29 10.05 10.05 249,660
Jul 6, 2026 9.60 9.77 9.20 9.62 9.62 288,088
Jul 2, 2026 9.70 9.96 9.45 9.60 9.60 318,024
Jul 1, 2026 9.68 9.85 9.34 9.55 9.55 308,466
Jun 30, 2026 10.11 10.48 9.71 9.77 9.77 600,346
Jun 29, 2026 10.16 10.44 9.64 10.09 10.09 497,436
Jun 26, 2026 9.45 10.25 9.43 10.21 10.21 3,221,427
Jun 25, 2026 9.08 9.65 9.01 9.46 9.46 440,829
Jun 24, 2026 9.63 10.09 9.02 9.12 9.12 351,859
Jun 23, 2026 8.89 9.70 8.78 9.65 9.65 711,994
Jun 22, 2026 9.10 9.23 8.85 9.00 9.00 356,302
Jun 18, 2026 9.60 9.73 8.90 9.02 9.02 492,124
Jun 17, 2026 9.20 9.83 9.06 9.40 9.40 283,580
Jun 16, 2026 9.64 9.64 9.00 9.10 9.10 322,103
Jun 15, 2026 9.65 9.79 9.37 9.64 9.64 172,462
Jun 12, 2026 9.10 10.22 9.04 9.50 9.50 564,583
Jun 11, 2026 9.11 9.24 8.96 9.00 9.00 200,386
Jun 10, 2026 8.67 9.34 8.58 9.11 9.11 284,893
Jun 9, 2026 8.68 9.00 8.43 8.69 8.69 324,139
Jun 8, 2026 9.18 9.44 8.43 8.50 8.50 260,161
Jun 5, 2026 9.04 9.23 8.85 9.08 9.08 262,518
Jun 4, 2026 9.00 9.39 8.84 9.07 9.07 219,177
Jun 3, 2026 9.08 9.09 8.48 9.00 9.00 499,732
Jun 2, 2026 9.81 9.82 8.50 9.23 9.23 583,777
Jun 1, 2026 9.28 9.88 8.99 9.82 9.82 330,038
May 29, 2026 9.12 9.46 8.94 9.10 9.10 290,711
May 28, 2026 8.98 9.25 8.72 9.11 9.11 179,212
May 27, 2026 8.99 9.98 8.74 8.98 8.98 624,445
May 26, 2026 8.30 9.05 8.22 8.97 8.97 570,692
May 22, 2026 8.07 8.42 8.00 8.16 8.16 294,996
May 21, 2026 7.82 8.24 7.72 8.06 8.06 517,775
May 20, 2026 7.38 8.16 7.38 7.98 7.98 658,503
May 19, 2026 7.14 7.50 6.85 7.47 7.47 411,283
May 18, 2026 7.66 8.04 7.08 7.14 7.14 572,015
May 15, 2026 8.80 9.09 7.50 7.67 7.67 998,049
May 14, 2026 9.53 10.23 8.70 8.90 8.90 1,008,998
May 13, 2026 8.99 9.03 8.57 8.85 8.85 953,906
May 12, 2026 8.84 9.25 8.73 8.91 8.91 275,585
May 11, 2026 8.64 9.27 8.45 8.81 8.81 466,729
May 8, 2026 8.87 9.00 8.54 8.64 8.64 295,536
May 7, 2026 8.96 9.00 8.68 8.85 8.85 168,967
May 6, 2026 9.61 9.61 9.02 9.02 9.02 180,401
May 5, 2026 9.31 9.52 9.21 9.41 9.41 201,784
May 4, 2026 8.75 9.55 8.67 9.30 9.30 325,300
May 1, 2026 8.35 8.83 8.25 8.77 8.77 229,786
Apr 30, 2026 8.44 8.66 8.17 8.31 8.31 317,432
Apr 29, 2026 8.59 8.59 8.11 8.40 8.40 264,676
Apr 28, 2026 8.66 8.93 8.50 8.60 8.60 229,547
Apr 27, 2026 8.99 9.22 8.57 8.66 8.66 464,701
Apr 24, 2026 8.77 8.89 8.40 8.66 8.66 267,905
Apr 23, 2026 9.61 9.61 8.71 8.75 8.75 545,797
Apr 22, 2026 9.31 9.66 9.11 9.55 9.55 486,145
Apr 21, 2026 8.94 9.60 8.61 9.17 9.17 954,217
Apr 20, 2026 8.54 9.00 8.26 8.94 8.94 185,839
Apr 17, 2026 8.89 8.89 8.46 8.61 8.61 165,540
Apr 16, 2026 8.62 8.94 8.42 8.66 8.66 226,070
Apr 15, 2026 8.60 8.81 8.40 8.56 8.56 348,031
Apr 14, 2026 8.40 8.57 8.30 8.45 8.45 562,963
Apr 13, 2026 7.96 8.87 7.87 8.28 8.28 1,019,996
Apr 10, 2026 8.16 8.24 7.81 8.00 8.00 451,573
Apr 9, 2026 7.22 8.25 7.19 8.16 8.16 1,201,960
Apr 8, 2026 7.36 7.72 7.08 7.25 7.25 487,249
Apr 7, 2026 6.22 7.25 5.96 7.21 7.21 1,037,364
Apr 6, 2026 5.90 6.55 5.85 6.32 6.32 538,614
Apr 2, 2026 5.61 6.10 5.49 5.89 5.89 185,498
Apr 1, 2026 5.61 5.86 5.39 5.82 5.82 587,680
Mar 31, 2026 5.31 5.75 5.31 5.57 5.57 505,537
Mar 30, 2026 5.40 5.57 5.25 5.30 5.30 829,735
Mar 27, 2026 5.51 5.77 5.40 5.48 5.48 847,250
Mar 26, 2026 5.08 5.61 5.00 5.57 5.57 4,207,983
Mar 25, 2026 5.36 5.71 5.09 5.21 5.21 1,655,277
Mar 24, 2026 6.03 6.50 5.14 5.44 5.44 17,851,885
Mar 23, 2026 7.34 7.58 6.57 6.66 6.66 967,060
Mar 20, 2026 7.76 9.04 7.43 7.63 7.63 1,496,158
Mar 19, 2026 8.33 8.62 7.73 7.73 7.73 759,748
Mar 18, 2026 8.35 8.68 7.96 8.40 8.40 501,706
Mar 17, 2026 8.58 8.60 7.97 8.38 8.38 702,875
Mar 16, 2026 7.86 8.63 7.86 8.55 8.55 574,209
Mar 13, 2026 7.91 8.26 7.29 7.85 7.85 696,861
Mar 12, 2026 8.70 8.90 7.64 7.90 7.90 912,271
Mar 11, 2026 8.20 8.85 7.96 8.75 8.75 461,085
Mar 10, 2026 8.94 8.94 8.21 8.23 8.23 605,333
Mar 9, 2026 8.78 8.96 8.25 8.49 8.49 735,911
Mar 6, 2026 8.72 9.11 8.57 8.77 8.77 725,196
Mar 5, 2026 9.13 9.17 8.68 8.82 8.82 509,407
Mar 4, 2026 9.12 9.54 8.96 9.15 9.15 397,719
Mar 3, 2026 9.57 9.59 9.03 9.13 9.13 1,718,600
Mar 2, 2026 9.16 9.83 8.75 9.59 9.59 507,469
Feb 27, 2026 9.30 9.55 9.02 9.41 9.41 529,989
Feb 26, 2026 10.09 10.11 9.16 9.35 9.35 576,151
Feb 25, 2026 10.21 10.38 9.95 10.09 10.09 479,494
Feb 24, 2026 10.03 10.99 9.78 10.07 10.07 613,359
Feb 23, 2026 9.61 10.38 9.45 10.03 10.03 591,834
Feb 20, 2026 9.70 9.81 9.40 9.67 9.67 312,602
Feb 19, 2026 9.20 9.80 9.01 9.67 9.67 593,222
Feb 18, 2026 9.64 9.82 9.14 9.25 9.25 754,662
Feb 17, 2026 8.63 9.94 8.41 9.40 9.40 896,727
Feb 13, 2026 8.98 9.45 8.11 8.58 8.58 2,252,516
Feb 12, 2026 6.72 9.94 6.72 8.94 8.94 2,752,822
Feb 11, 2026 6.58 7.38 6.28 7.37 7.37 593,479
Feb 10, 2026 6.28 6.70 6.20 6.59 6.59 281,701
Feb 9, 2026 6.30 6.60 5.90 6.31 6.31 561,340
Feb 6, 2026 6.22 6.66 6.00 6.26 6.26 520,595
Feb 5, 2026 6.43 6.97 6.02 6.09 6.09 608,432
Feb 4, 2026 6.56 6.70 6.05 6.30 6.30 272,912
Feb 3, 2026 6.33 6.88 6.25 6.55 6.55 485,463
Feb 2, 2026 6.52 6.68 6.22 6.31 6.31 297,838
Jan 30, 2026 6.66 6.80 6.42 6.52 6.52 267,962
Jan 29, 2026 6.95 7.08 6.61 6.63 6.63 176,731
Jan 28, 2026 7.03 7.20 6.91 6.92 6.92 304,312
Jan 27, 2026 6.70 7.14 6.51 7.05 7.05 433,343
Jan 26, 2026 6.58 6.82 6.36 6.65 6.65 318,490
Jan 23, 2026 6.70 7.09 6.54 6.59 6.59 323,421
Jan 22, 2026 6.35 6.64 6.08 6.64 6.64 358,104
Jan 21, 2026 5.96 6.49 5.88 6.32 6.32 482,170
Jan 20, 2026 6.19 6.33 5.89 5.95 5.95 424,245
Jan 16, 2026 6.80 6.85 6.25 6.31 6.31 398,571
Jan 15, 2026 7.17 7.24 6.49 6.66 6.66 445,237
Jan 14, 2026 7.90 8.07 7.15 7.19 7.19 750,297
Jan 13, 2026 8.19 8.27 7.57 7.91 7.91 282,041
Jan 12, 2026 8.64 8.64 7.05 8.20 8.20 603,517
Jan 9, 2026 8.29 8.95 8.11 8.68 8.68 904,249
Jan 8, 2026 7.91 8.42 7.72 8.17 8.17 518,712
Jan 7, 2026 7.39 8.15 7.39 7.87 7.87 652,561
Jan 6, 2026 7.40 7.50 7.29 7.35 7.35 418,119
Jan 5, 2026 7.22 7.42 7.10 7.40 7.40 379,365
Jan 2, 2026 7.44 7.44 7.01 7.19 7.19 141,513
Dec 31, 2025 7.31 7.43 7.30 7.36 7.36 141,557
Dec 30, 2025 7.38 7.52 7.16 7.31 7.31 941,083
Dec 29, 2025 7.37 7.49 7.12 7.34 7.34 158,548
Dec 26, 2025 7.50 7.50 7.16 7.44 7.44 106,297
Dec 24, 2025 7.44 7.54 7.32 7.47 7.47 77,163
Dec 23, 2025 7.27 7.55 7.14 7.44 7.44 237,380
Dec 22, 2025 7.00 7.70 6.92 7.27 7.27 370,972
Dec 19, 2025 6.44 7.09 6.44 6.94 6.94 580,136
Dec 18, 2025 6.04 6.77 6.04 6.37 6.37 177,736
Dec 17, 2025 6.36 6.77 5.99 6.02 6.02 149,218
Dec 16, 2025 6.68 6.80 6.33 6.33 6.33 148,543
Dec 15, 2025 6.96 7.00 6.59 6.71 6.71 140,360
Dec 12, 2025 7.07 7.48 6.85 6.95 6.95 222,149
Dec 11, 2025 6.52 7.05 6.35 7.00 7.00 596,439
Dec 10, 2025 6.35 6.69 6.19 6.48 6.48 160,882
Dec 9, 2025 5.89 6.51 5.89 6.39 6.39 360,906
Dec 8, 2025 5.84 6.01 5.70 5.89 5.89 148,614
Dec 5, 2025 5.95 5.95 5.74 5.75 5.75 64,491
Dec 4, 2025 5.41 6.04 5.37 5.91 5.91 134,739
Dec 3, 2025 5.36 5.52 5.30 5.46 5.46 288,881
Dec 2, 2025 5.71 5.80 5.34 5.36 5.36 120,821
Dec 1, 2025 5.60 6.15 5.48 5.75 5.75 256,800
Nov 28, 2025 5.46 5.71 5.46 5.62 5.62 45,688
Nov 26, 2025 5.49 5.66 5.37 5.55 5.55 113,030
Nov 25, 2025 5.58 5.67 5.31 5.45 5.45 118,422
Nov 24, 2025 5.88 5.93 5.56 5.56 5.56 103,126
Nov 21, 2025 5.64 5.95 5.60 5.90 5.90 61,567
Nov 20, 2025 6.09 6.10 5.70 5.76 5.76 102,892
Nov 19, 2025 6.30 6.50 5.80 5.98 5.98 220,267
Nov 18, 2025 5.73 6.43 5.73 6.24 6.24 131,748
Nov 17, 2025 5.68 6.06 5.53 5.79 5.79 142,606
Nov 14, 2025 5.40 5.85 5.40 5.68 5.68 95,335
Nov 13, 2025 5.55 5.70 5.35 5.50 5.50 56,838
Nov 12, 2025 5.42 5.65 5.41 5.59 5.59 56,586
Nov 11, 2025 5.34 5.71 5.25 5.46 5.46 69,674
Nov 10, 2025 5.17 5.45 5.14 5.44 5.44 70,238
Nov 7, 2025 5.22 5.28 5.01 5.16 5.16 91,770
Nov 6, 2025 5.43 5.45 5.09 5.22 5.22 94,401
Nov 5, 2025 5.61 5.71 5.34 5.36 5.36 65,422
Nov 4, 2025 6.00 6.00 5.41 5.65 5.65 190,589
Nov 3, 2025 5.80 6.17 5.66 6.07 6.07 198,187
Oct 31, 2025 5.97 6.10 5.75 5.80 5.80 167,929
Oct 30, 2025 5.96 6.29 5.95 5.96 5.96 80,346
Oct 29, 2025 6.36 6.40 6.03 6.08 6.08 154,606
Oct 28, 2025 6.43 6.60 6.30 6.33 6.33 108,045
Oct 27, 2025 6.34 6.50 6.09 6.42 6.42 128,757
Oct 24, 2025 6.28 6.39 6.11 6.34 6.34 84,549
Oct 23, 2025 6.20 6.40 6.13 6.19 6.19 90,303
Oct 22, 2025 6.47 6.75 5.71 6.14 6.14 331,668
Oct 21, 2025 6.45 6.60 6.18 6.43 6.43 83,134
Oct 20, 2025 5.93 6.70 5.93 6.47 6.47 254,920
Oct 17, 2025 6.03 6.03 5.75 5.93 5.93 49,886
Oct 16, 2025 6.07 6.07 5.83 6.03 6.03 151,435
Oct 15, 2025 6.01 6.22 5.85 5.95 5.95 179,377
Oct 14, 2025 5.61 6.06 5.51 5.77 5.77 207,614
Oct 13, 2025 6.01 6.15 5.60 5.62 5.62 171,769
Oct 10, 2025 5.91 5.95 5.50 5.50 5.50 217,730
Oct 9, 2025 5.61 6.09 5.52 5.82 5.82 651,786
Oct 8, 2025 4.75 6.11 4.51 5.90 5.90 3,132,554
Oct 7, 2025 6.15 6.29 5.52 5.77 5.77 133,897
Oct 6, 2025 6.38 6.68 6.15 6.16 6.16 51,798
Oct 3, 2025 6.29 6.58 6.19 6.38 6.38 47,457
Oct 2, 2025 6.23 6.45 6.17 6.29 6.29 35,793
Oct 1, 2025 6.30 6.70 6.13 6.21 6.21 69,309
Sep 30, 2025 6.35 6.62 6.08 6.54 6.54 44,367
Sep 29, 2025 6.50 6.76 6.33 6.35 6.35 55,578
Sep 26, 2025 6.64 6.64 6.28 6.55 6.55 48,569
Sep 25, 2025 6.77 7.18 6.66 6.66 6.66 40,123
Sep 24, 2025 7.68 7.90 6.80 6.88 6.88 145,889
Sep 23, 2025 5.85 7.89 5.63 7.48 7.48 474,910
Sep 22, 2025 5.49 5.92 5.32 5.85 5.85 149,628

Open, high, low and close are the prices as traded. Adjusted close accounts for splits and dividends, and is what the chart and returns use. Where a company changed its ticker, its history under the old symbol is included.

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Karyopharm Therapeutics Inc. Executive Compensation

We estimate that -- received a compensation of -- in --, making them the highest paid executive at KPTI, per a recent SEC DEF 14A filing.



Name
Role
Salary
Bonus
Stock/Option Awards
Total Compensation