Ionis Pharmaceuticals, Inc. Common Stock
IONS Real Time Price USDRecent trades of IONS by members of U.S. Congress
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Recently reported changes in IONS holdings by institutional investors
Quarterly net insider trading by IONS's directors and management
* Insider trading data parsed from SEC Form 4 filings by Quiver Quantitative. Sign up for the Quiver API for real-time access.
- 1M
- 3M
- 6M
- YTD
- 1Y
- 2Y
- 5Y
- MAX
About
Key Metrics
Return (1d)
Return (30d)
Return (1Y)
CAGR (Total)
Max Drawdown
Beta
Alpha
Sharpe Ratio
Win Rate
Average Win
Average Loss
Annual Volatility
Annual Std Dev
Information Ratio
Treynor Ratio
Total Trades
Metrics Definitions
Disclaimer: The performance results shown are based on historical backtesting and are hypothetical in nature. Backtested performance does not represent actual trading and does not account for all market factors that may affect execution, such as liquidity, slippage, and changing market conditions. Past performance is not necessarily indicative of future results. There is no guarantee that any trading strategy will be profitable or avoid losses.
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Alpha
Measures a portfolio's risk-adjusted performance against that of its benchmark
Learn More about Alpha -
Annual Standard Deviation
Measures how much the portfolio's total return varies from its mean or average.
Learn More about Annual Standard Deviation -
Annual Volatility
A statistical measure of the dispersion of returns for the portfolio.
Learn More about Annual Volatility -
Average Win
The average return (%) for trades that resulted in a positive return.
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Average Loss
The average return (%) for trades that resulted in a negative return.
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Beta
A measure of the volatility of the portfolio compared to the market as a whole.
Learn More about Beta -
CAGR
CAGR (Compounded Annual Growth Rate), is the historical annualized rate of return for an investment strategy, throughout the backtest period.
Learn More about CAGR -
Information Ratio
A measurement of portfolio returns beyond the returns of its benchmark compared to the volatility of those returns.
Learn More about Information Ratio -
Max Drawdown
the maximum observed loss from a peak to a trough of a portfolio, before a new peak is attained.
Learn More about Max Drawdown -
Sharpe Ratio
The Sharpe Ratio is a measure of historical risk-adjusted return, which quantifies the amount of return that an investor received per unit of risk.
Learn More about Sharpe Ratio -
Total Trades
The total number of trades made by this strategy.
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Treynor Ratio
Attempts to measure how successful an investment is in providing compensation to investors for taking on investment risk.
Learn More about Treynor Ratio -
Win Rate
The percentage of total trades that resulted in a positive return.
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Government lobbying spending instances
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$150,000 Jul 17, 2026 Issue: Medicare/Medicaid Taxation/Internal Revenue Code Health Issues
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$150,000 Apr 09, 2026 Issue: Health Issues Medicare/Medicaid Taxation/Internal Revenue Code
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$140,000 Jan 18, 2026 Issue: Health Issues Medicare/Medicaid Taxation/Internal Revenue Code
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$140,000 Oct 15, 2025 Issue: Health Issues Medicare/Medicaid Taxation/Internal Revenue Code
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$90,000 Jul 16, 2025 Issue: Health Issues Medicare/Medicaid Taxation/Internal Revenue Code
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$90,000 Apr 16, 2025 Issue: Health Issues Medicare/Medicaid Taxation/Internal Revenue Code
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$80,000 Jan 16, 2025 Issue: Health Issues Medicare/Medicaid Taxation/Internal Revenue Code
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$80,000 Oct 15, 2024 Issue: Taxation/Internal Revenue Code Medicare/Medicaid Health Issues
Former government officials who have lobbied for IONS
4 former government officials from 4 congressional offices at 2 lobbying firms have lobbied for IONS, most recently Jul 05, 2026.
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Alanna Temme House Legislative Director, U.S. Representative Jon Porter -
Sophie Khanahmadi House Legislative Asst., Rep. Martha Roby; Legislative Asst., Rep. Lee Terry; Staff Asst./LC, Senator Jeff Sessions -
Elizabeth Greer House New Chief of Staff, Rep. Allen Boyd (2001-2009) -
Barrett Thornhill Senate New Legislative Assistant, Sen. Mike Crapo (2003-2006)
IONS Estimated quarterly lobbying spending
IONS Revenue by Segment or Geography
New IONS patent grants
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Patent Title: Compounds and methods for reducing fus expression Sep. 15, 2026
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Patent Title: Modulation of tmprss6 expression Aug. 08, 2017
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Patent Title: 5′-end derivatives Aug. 08, 2017
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Patent Title: Compositions and methods Jul. 25, 2017
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Patent Title: Compositions comprising alternating 2′-modified nucleosides for use in gene modulation Jul. 18, 2017
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Patent Title: Method of preparing oligomeric compounds using modified coupling protocols Jul. 11, 2017
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Patent Title: Competitive modulation of micrornas Jul. 04, 2017
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Patent Title: Oligomeric compounds comprising bicyclic nucleosides and uses thereof Jul. 04, 2017
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Patent Title: Bicyclic morpholino compounds and oligomeric compounds prepared therefrom Jun. 27, 2017
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Patent Title: Modulation of huntingtin expression Jun. 20, 2017
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Patent Title: Compositions for modulating tau expression Jun. 20, 2017
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Patent Title: Modulation of hepatitis b virus (hbv) expression Jun. 13, 2017
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Patent Title: Modulation of prekallikrein (pkk) expression Jun. 06, 2017
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Patent Title: Modulation of alpha synuclein expression May. 30, 2017
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Patent Title: Methods for treating hypercholesterolemia May. 16, 2017
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Patent Title: Compositions and methods for modulating tau expression May. 09, 2017
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Patent Title: Modulation of apolipoprotein c-iii expression Apr. 18, 2017
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Patent Title: Compounds and methods for modulating gene expression Apr. 11, 2017
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Patent Title: Modulation of ube3a-ats expression Apr. 11, 2017
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Patent Title: Compositions for modulating c9orf72 expression Mar. 28, 2017
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Patent Title: Compounds and methods for modulating protein expression Mar. 28, 2017
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Patent Title: Oligomeric compounds and compositions for the use in modulation of micrornas Mar. 21, 2017
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Patent Title: Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations Mar. 14, 2017
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Patent Title: Methods and compositions for modulating apolipoprotein (a) expression Feb. 21, 2017
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Patent Title: Modulation of androgen receptor expression Feb. 14, 2017
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Patent Title: Antisense modulation of gccr expression Feb. 14, 2017
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Patent Title: Regulation of epigenetic control of gene expression Jan. 24, 2017
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Patent Title: Antisense compounds Jan. 24, 2017
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Patent Title: Methods for modulating metastasis-associated-in-lung-adenocarcinoma-transcript-1 (malat-1) expression Jan. 17, 2017
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Patent Title: Cancer treatment Jan. 10, 2017
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Patent Title: Methods of treating kennedy's disease Dec. 20, 2016
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Patent Title: Modulation of enhancer rna mediated gene expression Dec. 13, 2016
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Patent Title: Compounds and methods for modulating interaction between proteins and target nucleic acids Dec. 13, 2016
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Patent Title: Antisense compounds targeting genes associated with fibronectin Nov. 08, 2016
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Patent Title: Antisense modulation of superoxide dismutase 1, soluble expression Oct. 25, 2016
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Patent Title: Oligomeric compounds comprising tricyclic nucleosides and methods for their use Aug. 30, 2016
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Patent Title: Cyclohexenyl nucleic acids analogs Aug. 09, 2016
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Patent Title: Antisense modulation of gcgr expression Aug. 02, 2016
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Patent Title: Antisense modulation of ptp1b expression Aug. 02, 2016
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Patent Title: Method of preparing oligomeric compounds using modified capping protocols Aug. 02, 2016
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Patent Title: Modulation of transthyretin expression Jul. 26, 2016
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Patent Title: Modulation of apolipoprotein c-iii expression Jun. 14, 2016
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Patent Title: Compositions and their uses directed to huntingtin May. 31, 2016
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Patent Title: Antisense compounds targeting genes associated with usher syndrome May. 31, 2016
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Patent Title: Methods and compositions for modulating alpha-1-antitrypsin expression May. 17, 2016
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Patent Title: Methods for modulating kallikrein (klkb1) expression Apr. 26, 2016
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Patent Title: Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Apr. 26, 2016
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Patent Title: Methods for modulating kallikrein (klkb1) expression Apr. 19, 2016
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Patent Title: Oligomeric compounds having at least one neutrally linked terminal bicyclic nucleoside Mar. 22, 2016
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Patent Title: Modulation of huntingtin expression Mar. 01, 2016
Federal grants, loans, and purchases
Estimated quarterly amount awarded to IONS from public contracts
Recent insights relating to IONS
Recent picks made for IONS stock on CNBC
ETFs with the largest estimated holdings in IONS
- ... Highest Price Target
- ... Median Price Target
- ... Lowest Price Target
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Analyst
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- Is $IONS stock a Buy, Sell, or Hold?
- What is the price target for $IONS stock?
* Analyst consensus is not financial advice. Please see our data disclaimers .
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Shareholder
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- Who owns $IONS stock?
- Who owns the most shares of $IONS stock?
- What funds own $IONS stock?
* These are estimates based on data taken from SEC filings. There may be inaccuracies due to parsing errors, accidental double-counting, incorrect classification of indirectly owned shares, or any other number of issues.
The Quiver Smart Score combines our data on Congress Trading, Lobbying, Insider Trading, CNBC Mentions and more to provide a comprehensive view of the strength of a stock's underlying data.
The Smart Score grades stocks on a scale of 1 (weakest) to 10 (strongest) based on the strength of the underlying data.Sign Up to view IONS Smart Score
See concise summaries of analyst reports, presenting both bullish and bearish arguments for a stock.
Example:
The Bulls Say summary highlights positive aspects of the stock.
The Bears Say summary points out potential risks and negative aspects of the stock.
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
- Address Carlsbad, CA
- Market Cap 7.6 billion
- Employees 1,402
- Industrial Classification Pharmaceutical Preparations
Ionis Pharmaceuticals, Inc. Common Stock (IONS) Historical Stock Prices
Ionis Pharmaceuticals, Inc. Common Stock (IONS) closed at $45.75 on September 22, 2026. Over the past year its adjusted close ranged from $44.44 to $86.50. Daily prices go back to January 2, 2014, 3,179 trading days in all.
- 1 month-23.42%
- 3 months-39.79%
- Year to date-42.17%
- 1 year-25.44%
- 3 years+7.12%
- 5 years+22.98%
- Max+14.75%
Quiver Premium charts IONS's full daily history since 2014 with each congressional purchase and sale and every open-market insider purchase marked on the price line, with hover details for each trade.
Upgrade to Premium| Date | Open | High | Low | Close | Adj. Close | Volume |
|---|---|---|---|---|---|---|
| Sep 22, 2026 | 44.96 | 46.13 | 44.44 | 45.75 | 45.75 | 4,236,217 |
| Sep 21, 2026 | 44.95 | 45.25 | 44.20 | 44.90 | 44.90 | 4,521,358 |
| Sep 18, 2026 | 46.75 | 46.75 | 44.27 | 44.44 | 44.44 | 7,369,358 |
| Sep 17, 2026 | 46.68 | 47.42 | 45.75 | 46.75 | 46.75 | 4,079,573 |
| Sep 16, 2026 | 47.38 | 47.59 | 44.66 | 44.84 | 44.84 | 7,958,214 |
| Sep 15, 2026 | 51.37 | 51.37 | 46.72 | 47.25 | 47.25 | 6,812,465 |
| Sep 14, 2026 | 54.88 | 55.50 | 51.31 | 51.44 | 51.44 | 5,974,753 |
| Sep 11, 2026 | 55.94 | 56.16 | 54.16 | 54.21 | 54.21 | 2,175,778 |
| Sep 10, 2026 | 55.75 | 55.77 | 54.91 | 55.65 | 55.65 | 3,057,309 |
| Sep 9, 2026 | 56.38 | 56.96 | 55.70 | 56.02 | 56.02 | 3,037,757 |
| Sep 8, 2026 | 52.15 | 57.43 | 52.15 | 56.71 | 56.71 | 9,175,745 |
| Sep 4, 2026 | 58.36 | 58.96 | 57.78 | 58.09 | 58.09 | 2,671,092 |
| Sep 3, 2026 | 60.42 | 60.42 | 57.47 | 58.13 | 58.13 | 4,347,907 |
| Sep 2, 2026 | 60.25 | 61.77 | 59.77 | 61.33 | 61.33 | 1,845,866 |
| Sep 1, 2026 | 60.37 | 60.99 | 59.78 | 59.88 | 59.88 | 1,872,594 |
| Aug 31, 2026 | 61.06 | 61.06 | 59.70 | 60.36 | 60.36 | 2,017,160 |
| Aug 28, 2026 | 60.62 | 61.69 | 60.35 | 61.05 | 61.05 | 1,850,852 |
| Aug 27, 2026 | 63.48 | 63.48 | 62.34 | 62.43 | 62.43 | 1,625,581 |
| Aug 26, 2026 | 63.50 | 63.55 | 62.44 | 63.36 | 63.36 | 2,152,847 |
| Aug 25, 2026 | 62.53 | 64.19 | 62.19 | 63.57 | 63.57 | 2,435,239 |
| Aug 24, 2026 | 60.53 | 62.07 | 59.70 | 62.04 | 62.04 | 2,207,101 |
| Aug 21, 2026 | 59.64 | 60.91 | 59.06 | 59.74 | 59.74 | 2,723,906 |
| Aug 20, 2026 | 60.02 | 60.41 | 58.60 | 58.76 | 58.76 | 2,124,846 |
| Aug 19, 2026 | 60.11 | 61.35 | 59.61 | 60.80 | 60.80 | 3,137,560 |
| Aug 18, 2026 | 58.41 | 60.19 | 58.02 | 59.62 | 59.62 | 3,192,640 |
| Aug 17, 2026 | 57.11 | 58.74 | 56.41 | 58.63 | 58.63 | 2,000,182 |
| Aug 14, 2026 | 55.16 | 57.24 | 55.16 | 57.24 | 57.24 | 1,353,737 |
| Aug 13, 2026 | 56.50 | 56.81 | 55.56 | 55.87 | 55.87 | 1,220,460 |
| Aug 12, 2026 | 55.01 | 57.06 | 54.91 | 56.53 | 56.53 | 1,999,667 |
| Aug 11, 2026 | 56.79 | 57.16 | 55.37 | 55.42 | 55.42 | 2,407,128 |
| Aug 10, 2026 | 56.10 | 57.66 | 56.10 | 56.94 | 56.94 | 2,399,897 |
| Aug 7, 2026 | 54.73 | 56.60 | 54.40 | 56.56 | 56.56 | 2,009,277 |
| Aug 6, 2026 | 54.59 | 55.42 | 54.02 | 54.49 | 54.49 | 2,592,317 |
| Aug 5, 2026 | 55.17 | 55.36 | 53.58 | 54.19 | 54.19 | 2,122,267 |
| Aug 4, 2026 | 54.85 | 55.22 | 53.87 | 55.07 | 55.07 | 2,688,216 |
| Aug 3, 2026 | 52.66 | 54.54 | 52.16 | 54.49 | 54.49 | 3,212,858 |
| Jul 31, 2026 | 53.33 | 53.33 | 51.28 | 51.77 | 51.77 | 2,570,536 |
| Jul 30, 2026 | 53.92 | 54.04 | 52.65 | 53.28 | 53.28 | 2,875,352 |
| Jul 29, 2026 | 55.09 | 55.35 | 53.50 | 54.04 | 54.04 | 3,129,432 |
| Jul 28, 2026 | 56.56 | 56.56 | 54.00 | 55.30 | 55.30 | 2,805,274 |
| Jul 27, 2026 | 56.92 | 57.09 | 55.79 | 55.96 | 55.96 | 2,584,895 |
| Jul 24, 2026 | 56.32 | 57.36 | 56.19 | 56.55 | 56.55 | 3,094,731 |
| Jul 23, 2026 | 53.71 | 57.48 | 53.35 | 55.87 | 55.87 | 3,834,344 |
| Jul 22, 2026 | 51.16 | 54.06 | 50.01 | 54.01 | 54.01 | 8,732,966 |
| Jul 21, 2026 | 52.75 | 54.13 | 52.26 | 53.39 | 53.39 | 3,074,069 |
| Jul 20, 2026 | 54.47 | 54.80 | 52.82 | 52.95 | 52.95 | 2,167,064 |
| Jul 17, 2026 | 54.10 | 54.69 | 53.76 | 54.39 | 54.39 | 2,572,809 |
| Jul 16, 2026 | 53.95 | 55.98 | 53.38 | 54.65 | 54.65 | 3,805,259 |
| Jul 15, 2026 | 54.48 | 54.88 | 53.51 | 54.73 | 54.73 | 3,577,545 |
| Jul 14, 2026 | 55.80 | 56.45 | 54.53 | 54.93 | 54.93 | 4,700,265 |
| Jul 13, 2026 | 57.91 | 57.91 | 56.11 | 56.75 | 56.75 | 5,097,949 |
| Jul 10, 2026 | 64.27 | 64.44 | 58.20 | 58.25 | 58.25 | 11,444,106 |
| Jul 9, 2026 | 67.78 | 70.35 | 64.10 | 64.27 | 64.27 | 20,447,626 |
| Jul 8, 2026 | 85.56 | 86.74 | 83.92 | 84.46 | 84.46 | 2,280,833 |
| Jul 7, 2026 | 84.42 | 86.67 | 82.95 | 86.33 | 86.33 | 2,646,707 |
| Jul 6, 2026 | 82.11 | 84.01 | 81.19 | 83.18 | 83.18 | 1,847,437 |
| Jul 2, 2026 | 79.53 | 81.99 | 79.11 | 81.80 | 81.80 | 2,301,899 |
| Jul 1, 2026 | 79.13 | 79.48 | 77.95 | 79.19 | 79.19 | 1,442,398 |
| Jun 30, 2026 | 81.17 | 81.24 | 79.21 | 79.29 | 79.29 | 2,380,302 |
| Jun 29, 2026 | 81.00 | 82.53 | 79.95 | 80.69 | 80.69 | 2,806,623 |
| Jun 26, 2026 | 78.80 | 82.63 | 78.80 | 81.18 | 81.18 | 3,828,331 |
| Jun 25, 2026 | 76.69 | 79.55 | 76.25 | 78.34 | 78.34 | 2,583,536 |
| Jun 24, 2026 | 76.40 | 79.00 | 76.03 | 76.52 | 76.52 | 2,485,706 |
| Jun 23, 2026 | 75.89 | 77.31 | 75.77 | 75.99 | 75.99 | 1,405,415 |
| Jun 22, 2026 | 74.85 | 76.56 | 74.12 | 75.89 | 75.89 | 1,956,125 |
| Jun 18, 2026 | 75.00 | 75.66 | 73.50 | 74.12 | 74.12 | 2,984,374 |
| Jun 17, 2026 | 73.09 | 75.12 | 72.55 | 74.31 | 74.31 | 1,788,351 |
| Jun 16, 2026 | 73.93 | 73.95 | 72.30 | 73.09 | 73.09 | 1,801,390 |
| Jun 15, 2026 | 73.49 | 74.27 | 72.88 | 73.96 | 73.96 | 1,506,352 |
| Jun 12, 2026 | 73.82 | 74.35 | 72.57 | 73.28 | 73.28 | 1,964,868 |
| Jun 11, 2026 | 73.34 | 74.47 | 72.76 | 73.82 | 73.82 | 2,234,438 |
| Jun 10, 2026 | 74.43 | 75.85 | 72.83 | 73.32 | 73.32 | 1,595,746 |
| Jun 9, 2026 | 74.77 | 75.79 | 73.53 | 74.58 | 74.58 | 1,568,661 |
| Jun 8, 2026 | 74.33 | 74.43 | 73.14 | 73.54 | 73.54 | 1,620,750 |
| Jun 5, 2026 | 75.24 | 75.96 | 73.81 | 74.48 | 74.48 | 1,982,003 |
| Jun 4, 2026 | 74.01 | 75.88 | 73.82 | 75.13 | 75.13 | 1,241,131 |
| Jun 3, 2026 | 72.68 | 74.12 | 72.02 | 73.82 | 73.82 | 1,303,889 |
| Jun 2, 2026 | 74.85 | 75.22 | 72.56 | 72.97 | 72.97 | 2,086,205 |
| Jun 1, 2026 | 75.67 | 76.19 | 74.70 | 75.38 | 75.38 | 1,467,682 |
| May 29, 2026 | 77.54 | 78.10 | 76.39 | 76.50 | 76.50 | 1,675,660 |
| May 28, 2026 | 76.58 | 78.00 | 75.34 | 77.33 | 77.33 | 1,603,088 |
| May 27, 2026 | 76.24 | 77.40 | 76.23 | 76.49 | 76.49 | 1,341,369 |
| May 26, 2026 | 76.00 | 76.74 | 74.73 | 76.07 | 76.07 | 1,279,224 |
| May 22, 2026 | 75.71 | 76.80 | 75.00 | 75.56 | 75.56 | 1,579,206 |
| May 21, 2026 | 74.76 | 76.48 | 74.21 | 75.78 | 75.78 | 2,295,157 |
| May 20, 2026 | 74.67 | 75.69 | 73.97 | 75.06 | 75.06 | 2,005,309 |
| May 19, 2026 | 72.76 | 74.15 | 72.00 | 73.84 | 73.84 | 1,519,490 |
| May 18, 2026 | 74.58 | 74.78 | 71.93 | 72.52 | 72.52 | 2,211,491 |
| May 15, 2026 | 75.89 | 75.93 | 73.32 | 74.23 | 74.23 | 2,119,183 |
| May 14, 2026 | 79.00 | 79.19 | 75.31 | 75.68 | 75.68 | 1,798,305 |
| May 13, 2026 | 75.67 | 78.03 | 75.08 | 77.60 | 77.60 | 1,360,373 |
| May 12, 2026 | 76.03 | 77.13 | 75.38 | 75.83 | 75.83 | 1,408,887 |
| May 11, 2026 | 76.03 | 77.01 | 74.85 | 75.38 | 75.38 | 1,533,667 |
| May 8, 2026 | 76.45 | 77.40 | 75.24 | 75.71 | 75.71 | 1,656,234 |
| May 7, 2026 | 76.56 | 76.56 | 74.87 | 76.02 | 76.02 | 1,885,704 |
| May 6, 2026 | 75.62 | 77.42 | 75.29 | 76.85 | 76.85 | 1,799,880 |
| May 5, 2026 | 75.84 | 76.96 | 74.82 | 75.25 | 75.25 | 850,248 |
| May 4, 2026 | 75.28 | 76.00 | 74.47 | 75.45 | 75.45 | 1,689,516 |
| May 1, 2026 | 74.86 | 76.17 | 72.94 | 75.28 | 75.28 | 1,821,465 |
| Apr 30, 2026 | 74.91 | 77.76 | 73.81 | 74.76 | 74.76 | 2,430,344 |
| Apr 29, 2026 | 72.06 | 74.95 | 71.30 | 74.83 | 74.83 | 3,675,234 |
| Apr 28, 2026 | 72.71 | 73.10 | 71.17 | 71.78 | 71.78 | 2,396,291 |
| Apr 27, 2026 | 74.04 | 75.10 | 72.21 | 72.23 | 72.23 | 2,311,634 |
| Apr 24, 2026 | 74.09 | 74.51 | 72.33 | 73.27 | 73.27 | 1,817,367 |
| Apr 23, 2026 | 74.96 | 76.06 | 73.23 | 74.09 | 74.09 | 1,377,408 |
| Apr 22, 2026 | 75.22 | 75.44 | 74.00 | 74.83 | 74.83 | 2,024,007 |
| Apr 21, 2026 | 75.87 | 75.96 | 73.80 | 74.78 | 74.78 | 1,818,784 |
| Apr 20, 2026 | 75.50 | 75.62 | 74.58 | 74.87 | 74.87 | 1,106,829 |
| Apr 17, 2026 | 75.66 | 76.33 | 74.95 | 75.71 | 75.71 | 1,719,446 |
| Apr 16, 2026 | 76.42 | 76.53 | 73.91 | 75.26 | 75.26 | 1,873,899 |
| Apr 15, 2026 | 77.10 | 77.18 | 75.77 | 76.82 | 76.82 | 1,288,372 |
| Apr 14, 2026 | 74.88 | 77.38 | 74.88 | 76.76 | 76.76 | 1,595,277 |
| Apr 13, 2026 | 75.17 | 77.17 | 74.56 | 74.95 | 74.95 | 1,650,871 |
| Apr 10, 2026 | 77.02 | 77.14 | 74.53 | 75.17 | 75.17 | 1,581,578 |
| Apr 9, 2026 | 74.98 | 76.97 | 74.62 | 76.43 | 76.43 | 1,200,978 |
| Apr 8, 2026 | 76.07 | 76.48 | 74.30 | 74.98 | 74.98 | 1,266,771 |
| Apr 7, 2026 | 74.05 | 74.27 | 72.42 | 73.89 | 73.89 | 1,118,312 |
| Apr 6, 2026 | 74.54 | 75.47 | 73.56 | 74.33 | 74.33 | 1,440,939 |
| Apr 2, 2026 | 73.74 | 75.13 | 73.35 | 74.79 | 74.79 | 1,791,632 |
| Apr 1, 2026 | 75.70 | 76.48 | 74.79 | 75.13 | 75.13 | 1,664,978 |
| Mar 31, 2026 | 73.64 | 75.92 | 73.45 | 75.09 | 75.09 | 1,852,352 |
| Mar 30, 2026 | 73.12 | 73.21 | 71.48 | 72.52 | 72.52 | 2,045,479 |
| Mar 27, 2026 | 74.00 | 74.05 | 71.86 | 72.15 | 72.15 | 1,948,364 |
| Mar 26, 2026 | 72.25 | 75.63 | 70.50 | 74.24 | 74.24 | 3,884,070 |
| Mar 25, 2026 | 70.68 | 73.61 | 70.68 | 72.70 | 72.70 | 2,994,308 |
| Mar 24, 2026 | 70.27 | 70.64 | 68.90 | 69.68 | 69.68 | 1,844,404 |
| Mar 23, 2026 | 72.25 | 73.15 | 70.67 | 70.79 | 70.79 | 2,198,127 |
| Mar 20, 2026 | 71.51 | 72.59 | 70.50 | 70.99 | 70.99 | 2,920,652 |
| Mar 19, 2026 | 71.40 | 71.94 | 70.51 | 71.32 | 71.32 | 2,247,918 |
| Mar 18, 2026 | 71.84 | 72.30 | 70.92 | 71.67 | 71.67 | 2,180,298 |
| Mar 17, 2026 | 72.35 | 73.30 | 71.92 | 72.33 | 72.33 | 1,985,030 |
| Mar 16, 2026 | 71.58 | 72.88 | 71.29 | 72.34 | 72.34 | 3,231,515 |
| Mar 13, 2026 | 73.21 | 74.16 | 70.42 | 71.19 | 71.19 | 1,972,137 |
| Mar 12, 2026 | 74.30 | 74.30 | 72.01 | 72.34 | 72.34 | 2,461,797 |
| Mar 11, 2026 | 75.15 | 76.00 | 74.54 | 74.79 | 74.79 | 1,895,367 |
| Mar 10, 2026 | 75.36 | 77.03 | 74.51 | 75.66 | 75.66 | 2,785,714 |
| Mar 9, 2026 | 73.50 | 75.63 | 73.45 | 75.36 | 75.36 | 3,215,157 |
| Mar 6, 2026 | 73.97 | 75.16 | 73.15 | 74.04 | 74.04 | 1,904,239 |
| Mar 5, 2026 | 78.16 | 79.04 | 74.27 | 75.16 | 75.16 | 2,969,830 |
| Mar 4, 2026 | 79.16 | 80.06 | 77.67 | 79.45 | 79.45 | 2,503,118 |
| Mar 3, 2026 | 80.42 | 81.40 | 78.50 | 78.66 | 78.66 | 2,045,143 |
| Mar 2, 2026 | 79.27 | 82.75 | 79.27 | 81.96 | 81.96 | 3,098,359 |
| Feb 27, 2026 | 80.59 | 82.10 | 80.06 | 81.15 | 81.15 | 2,773,689 |
| Feb 26, 2026 | 80.32 | 82.44 | 78.92 | 80.60 | 80.60 | 3,330,043 |
| Feb 25, 2026 | 81.75 | 85.11 | 80.47 | 80.93 | 80.93 | 3,188,709 |
| Feb 24, 2026 | 84.66 | 85.47 | 83.45 | 85.45 | 85.45 | 2,384,832 |
| Feb 23, 2026 | 82.71 | 84.96 | 82.71 | 84.60 | 84.60 | 1,724,186 |
| Feb 20, 2026 | 82.85 | 83.63 | 81.64 | 83.15 | 83.15 | 2,832,477 |
| Feb 19, 2026 | 81.50 | 83.33 | 80.39 | 83.14 | 83.14 | 2,023,972 |
| Feb 18, 2026 | 81.26 | 83.06 | 80.98 | 82.22 | 82.22 | 1,950,099 |
| Feb 17, 2026 | 80.30 | 82.53 | 80.23 | 81.36 | 81.36 | 1,889,525 |
| Feb 13, 2026 | 81.18 | 82.56 | 79.78 | 80.60 | 80.60 | 1,931,201 |
| Feb 12, 2026 | 84.20 | 84.91 | 81.20 | 81.78 | 81.78 | 1,734,659 |
| Feb 11, 2026 | 84.19 | 84.96 | 82.00 | 84.35 | 84.35 | 1,104,176 |
| Feb 10, 2026 | 84.49 | 84.81 | 83.57 | 84.29 | 84.29 | 1,382,673 |
| Feb 9, 2026 | 86.13 | 86.49 | 84.61 | 84.79 | 84.79 | 1,738,204 |
| Feb 6, 2026 | 84.85 | 86.59 | 84.17 | 86.50 | 86.50 | 1,996,521 |
| Feb 5, 2026 | 84.51 | 86.74 | 82.89 | 83.48 | 83.48 | 2,677,732 |
| Feb 4, 2026 | 85.72 | 85.95 | 82.55 | 84.99 | 84.99 | 3,010,014 |
| Feb 3, 2026 | 83.00 | 85.45 | 83.00 | 84.59 | 84.59 | 1,461,130 |
| Feb 2, 2026 | 82.54 | 83.35 | 81.90 | 83.07 | 83.07 | 1,788,931 |
| Jan 30, 2026 | 83.48 | 83.70 | 82.21 | 82.67 | 82.67 | 2,518,439 |
| Jan 29, 2026 | 82.38 | 84.30 | 81.89 | 83.88 | 83.88 | 1,646,754 |
| Jan 28, 2026 | 81.92 | 82.63 | 81.62 | 81.92 | 81.92 | 1,732,406 |
| Jan 27, 2026 | 81.01 | 82.52 | 81.01 | 82.14 | 82.14 | 2,338,625 |
| Jan 26, 2026 | 79.49 | 81.28 | 79.24 | 81.00 | 81.00 | 1,700,602 |
| Jan 23, 2026 | 81.71 | 82.20 | 79.11 | 80.28 | 80.28 | 2,128,921 |
| Jan 22, 2026 | 79.62 | 82.19 | 78.89 | 81.79 | 81.79 | 3,695,674 |
| Jan 21, 2026 | 77.09 | 79.54 | 77.01 | 79.44 | 79.44 | 3,298,663 |
| Jan 20, 2026 | 75.03 | 77.99 | 74.20 | 77.53 | 77.53 | 4,894,345 |
| Jan 16, 2026 | 77.14 | 78.00 | 74.49 | 76.33 | 76.33 | 3,000,587 |
| Jan 15, 2026 | 79.25 | 79.75 | 77.15 | 77.21 | 77.21 | 1,409,021 |
| Jan 14, 2026 | 79.04 | 79.57 | 77.69 | 78.87 | 78.87 | 2,121,498 |
| Jan 13, 2026 | 82.24 | 82.57 | 78.61 | 79.48 | 79.48 | 1,885,179 |
| Jan 12, 2026 | 80.50 | 82.21 | 78.88 | 81.66 | 81.66 | 1,570,607 |
| Jan 9, 2026 | 82.17 | 83.23 | 79.30 | 80.30 | 80.30 | 2,668,760 |
| Jan 8, 2026 | 83.17 | 83.79 | 79.94 | 81.54 | 81.54 | 2,051,548 |
| Jan 7, 2026 | 82.50 | 86.15 | 82.40 | 83.17 | 83.17 | 3,889,646 |
| Jan 6, 2026 | 78.89 | 81.54 | 78.00 | 81.49 | 81.49 | 2,651,738 |
| Jan 5, 2026 | 79.18 | 79.42 | 76.08 | 78.53 | 78.53 | 1,448,687 |
| Jan 2, 2026 | 79.88 | 80.21 | 78.02 | 79.67 | 79.67 | 1,400,448 |
| Dec 31, 2025 | 78.78 | 79.84 | 78.63 | 79.11 | 79.11 | 1,096,900 |
| Dec 30, 2025 | 79.50 | 79.99 | 78.52 | 78.97 | 78.97 | 1,146,166 |
| Dec 29, 2025 | 79.73 | 80.04 | 78.74 | 79.98 | 79.98 | 1,077,894 |
| Dec 26, 2025 | 80.15 | 80.42 | 79.18 | 79.93 | 79.93 | 725,281 |
| Dec 24, 2025 | 80.33 | 81.02 | 80.33 | 80.65 | 80.65 | 480,227 |
| Dec 23, 2025 | 80.61 | 81.84 | 79.63 | 80.33 | 80.33 | 1,229,924 |
| Dec 22, 2025 | 79.26 | 82.09 | 79.09 | 81.34 | 81.34 | 2,257,844 |
| Dec 19, 2025 | 77.80 | 79.83 | 77.63 | 79.57 | 79.57 | 3,557,484 |
| Dec 18, 2025 | 77.39 | 78.16 | 76.69 | 77.63 | 77.63 | 1,765,565 |
| Dec 17, 2025 | 78.77 | 79.49 | 77.07 | 77.08 | 77.08 | 2,146,201 |
| Dec 16, 2025 | 79.41 | 79.56 | 77.16 | 78.37 | 78.37 | 1,959,742 |
| Dec 15, 2025 | 80.35 | 81.00 | 79.31 | 79.76 | 79.76 | 1,977,626 |
| Dec 12, 2025 | 79.19 | 80.92 | 78.50 | 80.82 | 80.82 | 1,468,893 |
| Dec 11, 2025 | 78.63 | 79.86 | 78.05 | 79.14 | 79.14 | 2,052,200 |
| Dec 10, 2025 | 79.38 | 79.71 | 77.79 | 78.63 | 78.63 | 2,659,323 |
| Dec 9, 2025 | 80.55 | 81.22 | 78.32 | 78.86 | 78.86 | 1,866,337 |
| Dec 8, 2025 | 82.12 | 82.86 | 81.18 | 81.51 | 81.51 | 1,553,583 |
| Dec 5, 2025 | 82.19 | 82.44 | 80.64 | 81.68 | 81.68 | 1,714,986 |
| Dec 4, 2025 | 81.90 | 83.61 | 81.44 | 81.81 | 81.81 | 2,317,827 |
| Dec 3, 2025 | 81.70 | 83.09 | 80.98 | 81.84 | 81.84 | 2,531,161 |
| Dec 2, 2025 | 82.38 | 82.69 | 80.00 | 81.31 | 81.31 | 2,454,566 |
| Dec 1, 2025 | 82.03 | 82.27 | 80.11 | 81.99 | 81.99 | 1,865,505 |
| Nov 28, 2025 | 82.59 | 82.95 | 81.67 | 82.73 | 82.73 | 852,943 |
| Nov 26, 2025 | 81.15 | 82.91 | 80.75 | 82.70 | 82.70 | 2,955,547 |
| Nov 25, 2025 | 78.52 | 81.20 | 78.33 | 80.93 | 80.93 | 2,543,172 |
| Nov 24, 2025 | 76.34 | 78.79 | 76.16 | 78.52 | 78.52 | 3,217,036 |
| Nov 21, 2025 | 73.00 | 76.31 | 73.00 | 76.09 | 76.09 | 2,076,032 |
| Nov 20, 2025 | 74.17 | 75.40 | 72.50 | 73.12 | 73.12 | 3,208,760 |
| Nov 19, 2025 | 74.55 | 75.00 | 71.83 | 74.00 | 74.00 | 3,620,815 |
| Nov 18, 2025 | 72.81 | 74.52 | 71.99 | 74.50 | 74.50 | 2,056,681 |
| Nov 17, 2025 | 70.70 | 74.42 | 70.69 | 73.26 | 73.26 | 3,504,705 |
| Nov 14, 2025 | 69.66 | 72.54 | 68.90 | 71.55 | 71.55 | 3,372,265 |
| Nov 13, 2025 | 72.56 | 73.05 | 68.22 | 69.84 | 69.84 | 11,502,846 |
| Nov 12, 2025 | 71.19 | 74.50 | 70.40 | 72.67 | 72.67 | 5,067,958 |
| Nov 11, 2025 | 69.32 | 72.79 | 68.55 | 72.45 | 72.45 | 2,268,649 |
| Nov 10, 2025 | 70.05 | 71.49 | 66.66 | 69.54 | 69.54 | 4,399,684 |
| Nov 7, 2025 | 73.58 | 75.00 | 72.36 | 73.55 | 73.55 | 2,332,419 |
| Nov 6, 2025 | 74.58 | 76.78 | 73.91 | 74.10 | 74.10 | 2,424,206 |
| Nov 5, 2025 | 72.14 | 75.08 | 71.48 | 74.68 | 74.68 | 2,259,305 |
| Nov 4, 2025 | 72.40 | 74.21 | 72.40 | 72.88 | 72.88 | 1,726,391 |
| Nov 3, 2025 | 74.77 | 75.25 | 71.95 | 73.65 | 73.65 | 2,576,035 |
| Oct 31, 2025 | 74.50 | 75.49 | 74.02 | 74.30 | 74.30 | 2,395,612 |
| Oct 30, 2025 | 71.91 | 74.70 | 71.66 | 74.17 | 74.17 | 2,177,727 |
| Oct 29, 2025 | 72.37 | 74.05 | 71.14 | 71.88 | 71.88 | 2,164,198 |
| Oct 28, 2025 | 72.99 | 74.04 | 72.50 | 73.57 | 73.57 | 2,559,568 |
| Oct 27, 2025 | 72.03 | 73.27 | 71.46 | 72.99 | 72.99 | 1,842,613 |
| Oct 24, 2025 | 72.39 | 72.44 | 70.22 | 70.86 | 70.86 | 1,990,370 |
| Oct 23, 2025 | 71.69 | 72.44 | 71.05 | 71.50 | 71.50 | 1,605,852 |
| Oct 22, 2025 | 71.23 | 71.98 | 70.60 | 71.50 | 71.50 | 1,508,356 |
| Oct 21, 2025 | 72.94 | 73.20 | 70.47 | 71.64 | 71.64 | 2,529,928 |
| Oct 20, 2025 | 73.55 | 73.69 | 72.30 | 73.55 | 73.55 | 1,395,624 |
| Oct 17, 2025 | 72.96 | 74.02 | 72.32 | 73.09 | 73.09 | 1,310,772 |
| Oct 16, 2025 | 73.12 | 74.42 | 72.07 | 73.07 | 73.07 | 1,739,636 |
| Oct 15, 2025 | 71.42 | 73.92 | 71.24 | 72.39 | 72.39 | 3,234,234 |
| Oct 14, 2025 | 70.59 | 72.15 | 70.08 | 71.37 | 71.37 | 1,264,896 |
| Oct 13, 2025 | 70.16 | 71.50 | 69.84 | 70.59 | 70.59 | 2,624,101 |
| Oct 10, 2025 | 70.00 | 70.49 | 69.40 | 69.97 | 69.97 | 1,697,166 |
| Oct 9, 2025 | 70.21 | 70.89 | 69.68 | 70.27 | 70.27 | 1,959,024 |
| Oct 8, 2025 | 70.49 | 71.87 | 69.60 | 69.96 | 69.96 | 3,102,776 |
| Oct 7, 2025 | 69.00 | 69.77 | 67.95 | 68.94 | 68.94 | 1,903,691 |
| Oct 6, 2025 | 69.15 | 70.14 | 68.85 | 69.02 | 69.02 | 1,824,037 |
| Oct 3, 2025 | 68.33 | 69.25 | 67.64 | 69.15 | 69.15 | 2,579,755 |
| Oct 2, 2025 | 66.21 | 68.41 | 65.97 | 68.40 | 68.40 | 2,999,333 |
| Oct 1, 2025 | 65.35 | 66.25 | 64.92 | 65.80 | 65.80 | 2,222,143 |
| Sep 30, 2025 | 63.90 | 65.55 | 63.66 | 65.42 | 65.42 | 2,140,270 |
| Sep 29, 2025 | 63.76 | 64.70 | 63.36 | 64.15 | 64.15 | 1,454,533 |
| Sep 26, 2025 | 64.03 | 64.49 | 63.05 | 64.09 | 64.09 | 1,522,295 |
| Sep 25, 2025 | 63.47 | 64.07 | 62.72 | 62.97 | 62.97 | 2,314,520 |
| Sep 24, 2025 | 62.65 | 63.99 | 62.19 | 63.94 | 63.94 | 1,592,919 |
| Sep 23, 2025 | 61.51 | 63.13 | 61.03 | 62.57 | 62.57 | 2,066,238 |
| Sep 22, 2025 | 63.18 | 63.18 | 61.05 | 61.36 | 61.36 | 2,682,881 |
Open, high, low and close are the prices as traded. Adjusted close accounts for splits and dividends, and is what the chart and returns use. Where a company changed its ticker, its history under the old symbol is included.
The Quiver API serves daily prices back to 2014 alongside congressional trades, insider trades, 13F holdings and lobbying, all under one key and inside Claude or ChatGPT through our MCP server.
Explore the Quiver APIWe estimate that -- received a compensation of -- in --, making them the highest paid executive at IONS, per a recent SEC DEF 14A filing. We estimate that the median employee at IONIS PHARMACEUTICALS INC is paid $220,397.
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