
PepGen Inc. Common Stock
PEPG
PEPG: PepGen Inc is a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapeutics with the goal of transforming the treatment of severe neuromuscular and neurologic diseases. The company has developed its Enhanced Delivery Oligonucleotide platform to improve the uptake and activity of conjugated oligonucleotide therapeutics. Its EDO peptides are engineered to optimize tissue penetration, cellular uptake, and nuclear delivery, and in preclinical studies, it is observed their ability to transport oligonucleotides into a broad range of target tissues, including smooth, skeletal, and cardiac muscle and the central nervous system. Its pipeline products are; PGN-EDO51, PGN-EDODM1, and others including PGN-EDO53 and PGN-EDO45.
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Patent Title: Antitumor and antiviral combination therapies using low-toxicity, long-circulating human interferon-alpha analogs Apr. 13, 2010
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Patent Title: Low-toxicity, long-circulating human interferon-alpha pegylated mutants Feb. 16, 2010
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