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Nurix Therapeutics, Inc. Common stock


NRIX: Nurix Therapeutics Inc is a biopharmaceutical company focused on the discovery, development and commercialization of oral, small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. The company's pipeline comprises targeted protein degraders of Brutons tyrosine kinase, or BTK, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, or CBL-B, an E3 ligase that regulates T cell activation. Its drug candidate from protein degradation portfolio, NX-2127, is an orally available BTK degrader for the treatment of relapsed or refractory B-cell malignancies. Its drug candidate from E3 ligase inhibitor portfolio, NX-1607, is an orally available CBL-B inhibitor for immuno-oncology indications.


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  • Patent Title: Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof Aug. 29, 2023
  • Patent Title: Cyano cyclobutyl compounds for cbl-b inhibition and uses thereof Dec. 20, 2022
  • Patent Title: Bifunctional compounds for degrading btk via ubiquitin proteosome pathway Oct. 25, 2022
  • Patent Title: 3-substituted piperidine compounds for cbl-b inhibition, and use thereof Oct. 11, 2022
  • Patent Title: Substituted benzyl-triazole compounds for cbl-b inhibition, and further uses thereof Aug. 02, 2022
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