Profusa jumps as CE-mark progress update appears to spark speculative buying

Profusa (PFSA) is up 42.9% today. Here is some analysis on what might have caused this price movement.

Analysis: The most likely catalyst is Profusa’s September 24 update showing progress toward a European CE mark for its Lumee Oxygen Platform, including a positive decision on ISO 13485 quality-system certification and an expectation that certification could arrive in early October. The move also appears to have been amplified by the stock’s very small share count and unusually heavy trading volume, which can intensify swings in micro-cap names.

Details:

Profusa said it received a positive decision from GMED regarding ISO 13485 certification of its quality management system, a step toward the remaining MDR conformity assessment work for Lumee.

The company said successful completion of the remaining assessment activities would support the applicable MDR certificate and a later CE mark for the Lumee Oxygen Platform in Europe.

At Profusa’s September 18 special meeting, the company said there were 605,647 common shares outstanding as of August 19, leaving a very limited share base that can magnify momentum trading.

Profusa had also recently disclosed that it regained compliance with Nasdaq’s bid-price and equity rules, which may have reduced an overhang tied to listing risk.

Sources:

Profusa, SEC, Nasdaq

Disclaimer: This price movement analysis was generated with the help of AI. Please double-check the information provided for mistakes.

$PFSA Insider Trading Activity

$PFSA insiders have traded $PFSA stock on the open market 11 times in the past 6 months. Of those trades, 6 have been purchases and 5 have been sales.

Here’s a breakdown of recent trading of $PFSA stock by insiders over the last 6 months:

FINANCIAL LP HRT has made 6 purchases buying 27,761 shares for an estimated $26,621 and 5 sales selling 64,393 shares for an estimated $150,373.

To track insider transactions, check out Quiver Quantitative's insider trading dashboard. You can access data on insider stock transactions through the Quiver Quantitative API insider transaction endpoint.

$PFSA Hedge Fund Activity

We have seen 8 institutional investors add shares of $PFSA stock to their portfolio, and 17 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

LEO WEALTH, LLC removed 149,092 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $75,589
RVW WEALTH, LLC removed 29,300 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $14,855
EWA, LLC removed 27,399 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $13,891
GABELLI FUNDS LLC removed 14,470 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $183,407
SG AMERICAS SECURITIES, LLC removed 13,500 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $6,844
GABELLI & CO INVESTMENT ADVISERS, INC. removed 10,530 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $133,467
HRT FINANCIAL LP added 6,838 shares (+inf%) to their portfolio in Q2 2026, for an estimated $79,662

To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.

This article is not financial advice. See Quiver Quantitative's disclaimers for more information. Note that there may be inaccuracies due to mistakes in ticker-mapping, and other anomalies.