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Ironwood Raises 2026 Guidance After Q2 Revenue Hits $113 Million

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Ironwood Pharmaceuticals (IRWD) reported second-quarter 2026 total revenue of $113.0 million, up from $85.2 million a year earlier. GAAP net income was $51.3 million, or $0.31 per share on both a basic and diluted basis.

The company raised its 2026 guidance, including total revenue of $460 million to $485 million and U.S. LINZESS net sales of $1.15 billion to $1.20 billion. Ironwood also said it repaid $200 million of convertible senior notes with cash on hand and began active recruiting for the confirmatory Phase 3 STARS-2 trial of apraglutide.

  • Q2 2026 LINZESS U.S. net sales were $282.3 million, up 14% from Q2 2025.
  • Adjusted EBITDA was $83.0 million, compared with $50.1 million a year earlier.
  • Cash and cash equivalents were $79.1 million at June 30, 2026.
  • Operating cash flow was $58.3 million in Q2 2026, compared with $15.1 million in Q2 2025.

$IRWD Insider Trading Activity

IRWD Insider Trades

$IRWD insiders have traded $IRWD stock on the open market 10 times in the past 6 months. Of those trades, 0 have been purchases and 10 have been sales.

Here’s a breakdown of recent trading of $IRWD stock by insiders over the last 6 months:

  • ALEXANDER J DENNER has made 0 purchases and 2 sales selling 6,730,800 shares for an estimated $20,530,448.
  • RONALD SILVER (PFO & PAO) has made 0 purchases and 3 sales selling 152,063 shares for an estimated $668,268.
  • MINARDO JOHN (Chief Legal Officer) has made 0 purchases and 2 sales selling 36,492 shares for an estimated $136,176.
  • MICHAEL SHETZLINE (SVP, CMO, Head-Res&Drug) has made 0 purchases and 2 sales selling 32,582 shares for an estimated $121,585.
  • JULIE MCHUGH sold 21,571 shares for an estimated $80,459

To track insider transactions, check out Quiver Quantitative's insider trading dashboard. You can access data on insider stock transactions through the Quiver Quantitative API insider transaction endpoint.

$IRWD Hedge Fund Activity

We have seen 114 institutional investors add shares of $IRWD stock to their portfolio, and 91 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.

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