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Insmed Q3 Revenue Reaches $524.4 Million as BRINSUPRI Sales Rise

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Insmed Incorporated (INSM) reported third-quarter 2026 product revenue of $524.4 million, up 268% from $142.3 million a year earlier. The company recorded a net loss of $100.3 million, or $0.46 per basic and diluted share, compared with a $370.0 million loss, or $1.75 per share, in the prior-year quarter.

BRINSUPRI revenue totaled $400.1 million during the quarter, while ARIKAYCE revenue was $124.4 million. Insmed raised its 2026 revenue guidance for both products.

  • BRINSUPRI revenue increased 29% from the second quarter of 2026.
  • ARIKAYCE revenue increased 9% from the third quarter of 2025.
  • 2026 BRINSUPRI revenue guidance was raised to $1.35 billion to $1.4 billion.
  • 2026 ARIKAYCE revenue guidance was raised to $460 million to $470 million.
  • Cash, cash equivalents and marketable securities totaled approximately $1.1 billion as of September 30, 2026.

$INSM Insider Trading Activity

INSM Insider Trades

$INSM insiders have traded $INSM stock on the open market 39 times in the past 6 months. Of those trades, 0 have been purchases and 39 have been sales.

Here’s a breakdown of recent trading of $INSM stock by insiders over the last 6 months:

  • ROGER ADSETT (Chief Operating Officer) has made 0 purchases and 3 sales selling 248,057 shares for an estimated $32,885,332.
  • WILLIAM LEWIS (Chair and CEO) has made 0 purchases and 17 sales selling 85,065 shares for an estimated $9,512,227.
  • MARTINA M.D. FLAMMER (Chief Medical Officer) has made 0 purchases and 11 sales selling 75,181 shares for an estimated $8,732,031.
  • DAVID R BRENNAN sold 25,000 shares for an estimated $3,100,000
  • MICHAEL ALEXANDER SMITH (Chief Legal Officer) has made 0 purchases and 4 sales selling 14,223 shares for an estimated $1,538,217.
  • SARA BONSTEIN (Chief Financial Officer) has made 0 purchases and 2 sales selling 10,676 shares for an estimated $1,206,898.
  • MELVIN MD SHAROKY sold 5,000 shares for an estimated $637,650

To track insider transactions, check out Quiver Quantitative's insider trading dashboard. You can access data on insider stock transactions through the Quiver Quantitative API insider transaction endpoint.

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$INSM Hedge Fund Activity

We have seen 384 institutional investors add shares of $INSM stock to their portfolio, and 329 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

  • JPMORGAN CHASE & CO added 10,428,170 shares (+inf%) to their portfolio in Q2 2026, for an estimated $1,111,851,485
  • DARWIN GLOBAL MANAGEMENT, LTD. removed 10,374,021 shares (-61.7%) from their portfolio in Q2 2026, for an estimated $1,106,078,119
  • ORBIS ALLAN GRAY LTD added 4,203,663 shares (+224.5%) to their portfolio in Q2 2026, for an estimated $448,194,549
  • AMERIPRISE FINANCIAL INC added 3,121,853 shares (+102.1%) to their portfolio in Q2 2026, for an estimated $332,851,966
  • FMR LLC added 2,983,416 shares (+22.7%) to their portfolio in Q2 2026, for an estimated $318,091,813
  • CAPITAL INTERNATIONAL INVESTORS added 2,642,930 shares (+47.2%) to their portfolio in Q2 2026, for an estimated $281,789,196
  • MAVERICK CAPITAL LTD added 2,150,762 shares (+inf%) to their portfolio in Q2 2026, for an estimated $229,314,244

To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.

$INSM Congressional Stock Trading

Members of Congress have traded $INSM stock 1 times in the past 6 months. Of those trades, 0 have been purchases and 1 have been sales.

Here’s a breakdown of recent trading of $INSM stock by members of Congress over the last 6 months:

To track congressional stock trading, check out Quiver Quantitative's congressional trading dashboard. You can access data on congressional stock trades through the Quiver Quantitative API Congress trades endpoint.

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