Esperion appoints John Harlow as Chief Commercial Officer to enhance sales and marketing strategies effective November 17, 2025.
Quiver AI Summary
Esperion has announced the appointment of John Harlow as Chief Commercial Officer, effective November 17, 2025. Harlow, who has over 20 years of experience in pharmaceutical leadership, will be part of Esperion’s Executive Leadership Team and will report to President and CEO Sheldon Koenig. His previous role was at Melinta Therapeutics, where he significantly grew the company's revenue and established a comprehensive commercial platform. Harlow has held senior roles at various pharmaceutical companies and has a strong background in commercial strategy, aiming to enhance sales and marketing performance for Esperion’s cardiovascular therapies. He expressed excitement about joining Esperion and contributing to the management of cardiovascular risk.
Potential Positives
- Appointment of John Harlow as Chief Commercial Officer signals strategic leadership aimed at enhancing sales and marketing performance, indicating a focus on growth and effectiveness in commercial strategies.
- Harlow brings over two decades of experience in the pharmaceutical sector, including a track record of driving significant revenue growth, which could enhance Esperion’s market position.
- His previous role at Melinta Therapeutics involved nearly doubling revenue, demonstrating his capability to implement successful business models that could be applied at Esperion.
- Harlow’s leadership is expected to accelerate the delivery of innovative cardiovascular risk reduction therapies to patients, aligning with Esperion’s mission to address unmet patient needs.
Potential Negatives
- John Harlow's previous role as Chief Commercial Officer at Melinta Therapeutics included significant revenue growth, which may put pressure on Esperion to replicate or exceed this performance.
- The press release includes forward-looking statements that carry associated risks and uncertainties, indicating potential volatility in future financial performance.
- Esperion's focus on innovative therapies indicates reliance on successful commercial execution, leaving the company vulnerable to delays or failures in product adoption and market penetration.
FAQ
Who was appointed as Esperion's Chief Commercial Officer?
John Harlow was appointed as the Chief Commercial Officer of Esperion effective November 17, 2025.
What previous experience does John Harlow bring to Esperion?
John Harlow has over two decades of executive leadership in the pharmaceutical industry, previously serving as CCO at Melinta Therapeutics and Baudax Bio.
What are NEXLETOL® and NEXLIZET®?
NEXLETOL® and NEXLIZET® are FDA-approved oral therapies developed by Esperion for patients at risk of cardiovascular disease.
What is Esperion's focus as a biopharmaceutical company?
Esperion focuses on developing innovative medicines that address unmet medical needs, particularly for cardiovascular disease management.
How can I learn more about Esperion?
More information can be found on Esperion's website at esperion.com and on their LinkedIn and X pages.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$ESPR Insider Trading Activity
$ESPR insiders have traded $ESPR stock on the open market 9 times in the past 6 months. Of those trades, 0 have been purchases and 9 have been sales.
Here’s a breakdown of recent trading of $ESPR stock by insiders over the last 6 months:
- SHELDON L. KOENIG (President and CEO) has made 0 purchases and 2 sales selling 58,901 shares for an estimated $113,050.
- BENJAMIN LOOKER (General Counsel) has made 0 purchases and 4 sales selling 15,241 shares for an estimated $29,715.
- BENJAMIN HALLADAY (Chief Financial Officer) has made 0 purchases and 3 sales selling 14,286 shares for an estimated $28,125.
To track insider transactions, check out Quiver Quantitative's insider trading dashboard.
$ESPR Hedge Fund Activity
We have seen 72 institutional investors add shares of $ESPR stock to their portfolio, and 78 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- BELLEVUE GROUP AG removed 9,694,064 shares (-100.0%) from their portfolio in Q2 2025, for an estimated $9,542,836
- MORGAN STANLEY removed 5,531,144 shares (-84.0%) from their portfolio in Q2 2025, for an estimated $5,444,858
- PENDERFUND CAPITAL MANAGEMENT LTD. added 4,676,519 shares (+233.8%) to their portfolio in Q2 2025, for an estimated $4,603,565
- TWO SEAS CAPITAL LP added 3,024,104 shares (+43.6%) to their portfolio in Q2 2025, for an estimated $2,976,927
- AIGH CAPITAL MANAGEMENT LLC added 3,000,000 shares (+inf%) to their portfolio in Q3 2025, for an estimated $7,950,000
- NUVEEN, LLC removed 2,665,087 shares (-86.3%) from their portfolio in Q2 2025, for an estimated $2,623,511
- MARSHALL WACE, LLP added 1,679,294 shares (+46.2%) to their portfolio in Q2 2025, for an estimated $1,653,097
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard.
$ESPR Analyst Ratings
Wall Street analysts have issued reports on $ESPR in the last several months. We have seen 1 firms issue buy ratings on the stock, and 0 firms issue sell ratings.
Here are some recent analyst ratings:
- HC Wainwright & Co. issued a "Buy" rating on 06/17/2025
To track analyst ratings and price targets for $ESPR, check out Quiver Quantitative's $ESPR forecast page.
Full Release
– Brings Extensive Executive Leadership Driving Commercial Strategies That Enhance Sales and Marketing Performance –
ANN ARBOR, Mich., Nov. 04, 2025 (GLOBE NEWSWIRE) -- Esperion (NASDAQ: ESPR) today announced the appointment of John Harlow as the Company’s Chief Commercial Officer, effective November 17, 2025. Mr. Harlow will join Esperion’s Executive Leadership Team and will report directly to Sheldon Koenig, President and CEO of Esperion.
"We are thrilled to welcome John as our Chief Commercial Officer at such a pivotal time in Esperion’s growth, as we continue to expand adoption of our products in the U.S. and increase our global footprint," said Koenig. "John’s deep domain expertise in building and scaling commercial organizations, combined with his proven success in driving revenue and leading high-performance teams, will be instrumental as we accelerate the delivery of our innovative cardiovascular risk reduction therapies to patients worldwide. His leadership will help ensure that our therapies reach the people who need it most."
Mr. Harlow is a seasoned executive with more than two decades of senior leadership at large, mid-size and start-up pharmaceutical companies across multiple therapeutic areas. He joins Esperion from Melinta Therapeutics where he served as Chief Commercial Officer from early 2021. During his tenure, he built a comprehensive commercial platform that transformed Melinta's business model and nearly doubled revenue delivering ~85% growth in 2024 from 2020, while leading a commercial team of ~80 full-time employees across sales, marketing, market access, trade, training, and operations. Previously, Mr. Harlow was Chief Commercial Officer at Baudax Bio and held commercial leadership roles of increasing responsibility at Recro Pharma, Inc., Endo Pharmaceuticals, Shionogi USA, Pfizer, Inc., Alpharma Inc., and Novartis. Earlier in his career, Mr. Harlow was an equity research analyst covering large cap pharmaceutical companies at Bank of America Merrill Lynch and started at Janssen Pharmaceuticals, Inc. as a sales representative and marketing communications specialist.
Mr. Harlow earned his M.B.A in Pharmaceutical Management and Marketing at Seton Hall University and his B.S. in Biology at Lehigh University.
“I’m incredibly excited to join Esperion at a time when the company is redefining cardiovascular disease prevention for millions of patients," said John Harlow, Chief Commercial Officer of Esperion. "Esperion’s commitment to innovation, its expanding global footprint, and the proven impact of its therapies, NEXLETOL ® (bempedoic acid) and NEXLIZET ® (bempedoic acid and ezetimibe), make this a unique opportunity to drive meaningful change in how we manage cardiovascular risk. I look forward to working with this talented team to accelerate growth and expand access to life-saving treatments."
About Esperion Therapeutics
Esperion Therapeutics, Inc. is a commercial stage biopharmaceutical company focused on bringing new medicines to market that address unmet needs of patients and healthcare professionals. The Company developed and is commercializing the only U.S. Food and Drug Administration (FDA) approved oral, once-daily, non-statin medicines for patients who are at risk for cardiovascular disease and are struggling with elevated low density lipoprotein cholesterol (LDL-C). These medications are supported by the nearly 14,000 patient CLEAR Cardiovascular Outcomes Trial. Esperion continues to build on its success with its next generation program which is focused on developing ATP citrate lyase inhibitors (ACLYi). New insights into the structure and function of ACLYi fully enables rational drug design and the opportunity to develop highly potent and specific inhibitors with allosteric mechanisms.
Esperion continues to evolve into a leading global biopharmaceutical company through commercial execution, international partnerships and collaborations and advancement of its pre-clinical pipeline. For more information, visit esperion.com and follow Esperion on LinkedIn and X .
Forward-Looking Statements
This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding marketing strategy and commercialization plans, expected profitability, future operations, commercial products, clinical development, and other statements containing the words “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “predict,” “project,” “suggest,” “target,” “potential,” “will,” “would,” “could,” “should,” “continue,” and similar expressions. Any express or implied statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Forward-looking statements involve risks and uncertainties that could cause Esperion’s actual results to differ significantly from those projected, including, without limitation, the net sales, profitability, and growth of Esperion’s commercial products, clinical activities and results, supply chain, commercial development and launch plans, the outcomes and anticipated benefits of legal proceedings and settlements, and the risks detailed in Esperion’s filings with the Securities and Exchange Commission. Any forward-looking statements contained in this press release speak only as of the date hereof, and Esperion disclaims any obligation or undertaking to update or revise any forward-looking statements contained in this press release, other than to the extent required by law.
Esperion Contact Information:
Investors:
Alina Venezia
[email protected]
(734) 887-3903
Media:
Tiffany Aldrich
[email protected]
(616) 443-8438