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AstraZeneca PLC (AZN) Releases Q4 2025 Earnings: Modest Revenue Growth and Strong Profitability Improvement

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AstraZeneca PLC (AZN) reported Q4 2025 results with revenue up modestly and strong improvement in profitability. Total revenue came in at $15.5 billion (up 4.11% year-over-year), while operating profit rose to $11.6 billion (up 469.16% YoY). Net income attributable to common shareholders was $2.3 billion (up 55.07% YoY) and diluted earnings per share was $0.75 (up 55.21% YoY).

  • Key income statement highlights:
  • Total revenue: $15.5 billion (+4.11% YoY)
  • Gross profit: $15.5 billion (+27.43% YoY)
  • Operating profit: $11.6 billion (+469.16% YoY)
  • Net income to common shareholders: $2.3 billion (+55.07% YoY)
  • Balance sheet and cash flow snapshots show solid liquidity but weaker operating cash conversion in the quarter.

  • Balance sheet and cash flow highlights:
  • Cash from operating activities: $2.3 billion (down 19.44% YoY)
  • Purchases of property, plant and equipment (capex): $1.0 billion (up 46.33% YoY)
  • Cash and cash equivalents: $5.7 billion (up 4.06% YoY)
  • Total liabilities: $65.4 billion (up 3.47% YoY)
  • Note: This financials data is sourced from a third-party provider and has not been independently verified by Quiver.

    AstraZeneca PLC Hedge Fund Activity

    We have seen 709 institutional investors add shares of AstraZeneca PLC stock to their portfolio, and 507 decrease their positions in their most recent quarter.

    Here are some of the largest recent moves:

    To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard.

    AstraZeneca PLC Government Contracts

    We have seen $1,293,572 of award payments to $AZN over the last year.

    Here are some of the awards which we have have seen pay out the most over the last year:

    To track government contracts to publicy traded companies, check out Quiver Quantitative's government contracts dashboard.

    AstraZeneca PLC Congressional Stock Trading

    Members of Congress have traded $AZN stock 8 times in the past 6 months. Of those trades, 5 have been purchases and 3 have been sales.

    Here’s a breakdown of recent trading of $AZN stock by members of Congress over the last 6 months:

    To track congressional stock trading, check out Quiver Quantitative's congressional trading dashboard.

    AstraZeneca PLC Analyst Ratings

    Wall Street analysts have issued reports on $AZN in the last several months. We have seen 1 firms issue buy ratings on the stock, and 0 firms issue sell ratings.

    Here are some recent analyst ratings:

    • Jefferies issued a "Buy" rating on 10/27/2025

    To track analyst ratings and price targets for AstraZeneca PLC, check out Quiver Quantitative's $AZN forecast page.

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