ZyVersa announces pipeline advancements with IC 100 for obesity-related inflammation and VAR 200 for diabetic kidney disease. Meetings welcomed.
Quiver AI Summary
ZyVersa Therapeutics, Inc. is progressing in developing innovative drug candidates using its proprietary technologies, including the Inflammasome ASC Inhibitor IC 100, aimed at reducing inflammation in conditions like obesity with metabolic complications, and the Cholesterol Efflux Mediator™ VAR 200 for addressing renal lipid and cholesterol issues linked to kidney disease, with a phase 2a trial for diabetic kidney disease expected to start in Q1-2025. CEO Stephen C. Glover will be participating in the JPM 2025 Healthcare Conference to engage with investors and stakeholders about the company’s differentiated pipeline and future opportunities. ZyVersa specializes in treatments for inflammatory and kidney diseases, and its products have significant market potential, with the overall opportunity exceeding $100 billion. For further information, ZyVersa invites inquiries and offers access to its innovative product pipeline online.
Potential Positives
- ZyVersa is developing two first-in-class drug candidates, which positions the company as an innovator in the biopharmaceutical space targeting inflammatory and renal diseases.
- The anticipated start of a Phase 2a clinical trial for VAR 200 in diabetic kidney disease by Q1 2025 demonstrates progress in their drug development pipeline, potentially leading to new treatment options for patients.
- The company's focus on obesity with metabolic complications as a lead indication for IC 100 addresses a significant health issue with high unmet medical needs, widening market potential.
- ZyVersa is participating in a prestigious industry event (JPM 2025), which offers opportunities for networking with strategic industry players and potential investors, enhancing their visibility in the market.
Potential Negatives
- The press release heavily relies on forward-looking statements, indicating significant uncertainty regarding the company's future performance and the success of its drug candidates, which may lead to investor skepticism.
- The announcement of ongoing and future clinical trials may raise concerns over the company's ability to achieve timely progress, especially with the notable absence of specific timelines for key developments beyond 2025.
- There is a lack of concrete data or results from past trials, which could lead to doubts about the effectiveness and viability of their drug candidates in a competitive market.
FAQ
What is ZyVersa Therapeutics?
ZyVersa Therapeutics is a clinical stage specialty biopharmaceutical company focused on developing first-in-class drugs for inflammatory and renal diseases.
What are the key drug candidates in ZyVersa's pipeline?
ZyVersa is advancing two primary drug candidates: Inflammasome ASC Inhibitor IC 100 and Cholesterol Efflux Mediator VAR 200.
What diseases does Inflammasome ASC Inhibitor IC 100 target?
IC 100 is designed to treat obesity with metabolic complications, particularly cardiovascular diseases.
When does the phase 2a clinical trial for VAR 200 begin?
The phase 2a clinical trial for VAR 200 is expected to start in Q1 2025, focusing on diabetic kidney disease.
How can investors meet with ZyVersa's CEO?
Investors can schedule one-on-one meetings with Stephen Glover by contacting Zach Glover at [email protected].
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$ZVSA Hedge Fund Activity
We have seen 5 institutional investors add shares of $ZVSA stock to their portfolio, and 6 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- TWO SIGMA SECURITIES, LLC removed 31,205 shares (-100.0%) from their portfolio in Q2 2024
- CUBIST SYSTEMATIC STRATEGIES, LLC removed 29,366 shares (-100.0%) from their portfolio in Q2 2024
- HRT FINANCIAL LP removed 13,176 shares (-100.0%) from their portfolio in Q2 2024
- JANE STREET GROUP, LLC removed 12,120 shares (-100.0%) from their portfolio in Q2 2024
- ADAR1 CAPITAL MANAGEMENT, LLC removed 9,598 shares (-100.0%) from their portfolio in Q3 2024
- TOWER RESEARCH CAPITAL LLC (TRC) added 1,867 shares (+267.1%) to their portfolio in Q3 2024
- UBS GROUP AG added 433 shares (+inf%) to their portfolio in Q3 2024
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard.
Full Release
- ZyVersa is advancing a pipeline of first-in-class drug candidates built around two proprietary technologies.
- Inflammasome ASC Inhibitor IC 100 designed to attenuate initiation and perpetuation of disease-causing inflammation; lead indication: obesity with metabolic complications (e.g., cardiovascular disease).
- Cholesterol Efflux Mediator™ VAR 200 designed to mediate removal of renal lipids and cholesterol that lead to kidney damage and disease; phase 2a clinical trial in diabetic kidney disease expected to begin Q1-2025.
- Mr. Glover welcomes one-on-one meetings to discuss ZyVersa’s technology, pipeline assets, and key development milestones.
WESTON, Fla., Dec. 18, 2024 (GLOBE NEWSWIRE) -- ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA; “ZyVersa”), a clinical stage specialty biopharmaceutical company developing first-in-class drugs for treatment of patients with inflammatory and renal diseases who have unmet medical needs, announces that Stephen C. Glover, Co-Founder, Chairman, Chief Executive Officer, and President, will attend JPM’s 43rd Annual Healthcare Conference 2025 being held January 13 – 16, 2025 in San Francisco.
“We look forward to meeting with industry strategics and investors during JPM 2025 to discuss the value building opportunities expected with our highly differentiated Inflammasome ASC Inhibitor IC 100 and Cholesterol Efflux Mediator TM VAR 200, said Stephen Glover.” To meet with Mr. Glover, please contact Zach Glover at [email protected].
To learn more about ZyVersa and its innovative and differentiated product pipeline, please visit www.zyversa.com .
About ZyVersa Therapeutics, Inc.
ZyVersa (Nasdaq: ZVSA) is a clinical stage specialty biopharmaceutical company leveraging advanced proprietary technologies to develop first-in-class drugs for patients with inflammatory or kidney diseases with high unmet medical needs. We are well positioned in the rapidly emerging inflammasome space with a highly differentiated monoclonal antibody, Inflammasome ASC Inhibitor IC 100, and in kidney disease with phase 2 Cholesterol Efflux Mediator TM VAR 200. The lead indication for IC 100 is obesity with metabolic complications, and for VAR 200, focal segmental glomerulosclerosis (FSGS). Each therapeutic area offers a “pipeline within a product,” with potential for numerous indications. The total accessible market is over $100 billion. For more information, please visit www.zyversa.com .
Cautionary Statement Regarding Forward-Looking Statements
Certain statements contained in this press release regarding matters that are not historical facts, are forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. These include statements regarding management’s intentions, plans, beliefs, expectations, or forecasts for the future, and, therefore, you are cautioned not to place undue reliance on them. No forward-looking statement can be guaranteed, and actual results may differ materially from those projected. ZyVersa Therapeutics, Inc. (“ZyVersa”) uses words such as “anticipates,” “believes,” “plans,” “expects,” “projects,” “future,” “intends,” “may,” “will,” “should,” “could,” “estimates,” “predicts,” “potential,” “continue,” “guidance,” and similar expressions to identify these forward-looking statements that are intended to be covered by the safe-harbor provisions. Such forward-looking statements are based on ZyVersa’s expectations and involve risks and uncertainties; consequently, actual results may differ materially from those expressed or implied in the statements due to a number of factors, including ZyVersa’s plans to develop and commercialize its product candidates, the timing of initiation of ZyVersa’s planned preclinical and clinical trials; the timing of the availability of data from ZyVersa’s preclinical and clinical trials; the timing of any planned investigational new drug application or new drug application; ZyVersa’s plans to research, develop, and commercialize its current and future product candidates; the clinical utility, potential benefits and market acceptance of ZyVersa’s product candidates; ZyVersa’s commercialization, marketing and manufacturing capabilities and strategy; ZyVersa’s ability to protect its intellectual property position; and ZyVersa’s estimates regarding future revenue, expenses, capital requirements and need for additional financing.
New factors emerge from time-to-time, and it is not possible for ZyVersa to predict all such factors, nor can ZyVersa assess the impact of each such factor on the business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. Forward-looking statements included in this press release are based on information available to ZyVersa as of the date of this presentation. ZyVersa disclaims any obligation to update such forward-looking statements to reflect events or circumstances after the date of this presentation, except as required by applicable law.
Corporate, IR, and Media Contact
Karen Cashmere
Chief Commercial Officer
[email protected]
786-251-9641