Pyxis Oncology (PYXS) reported a second-quarter 2026 net loss of $25.3 million, or $0.40 per common share, compared with a $18.4 million loss, or $0.30 per share, a year earlier. The company reported no milestone revenue in the quarter.
Cash, cash equivalents, restricted cash and short-term investments totaled $34.5 million as of June 30. Pyxis completed a private placement on July 2 that generated approximately $50 million in upfront gross proceeds and said its cash runway extends into the second quarter of 2027.
- Research and development expense was $16.1 million, compared with $17.1 million a year earlier.
- General and administrative expense was $9.9 million, up from $5.4 million.
- Pyxis expects updated MICVO monotherapy data in recurrent or metastatic head and neck cancer in fall 2026.
- Updated data from the MICVO and pembrolizumab combination study are expected in the fourth quarter of 2026.
- The private placement could generate up to an additional approximately $64 million in gross proceeds if accompanying warrants are exercised for cash.
$PYXS Hedge Fund Activity
We have seen 25 institutional investors add shares of $PYXS stock to their portfolio, and 46 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- ATLE FUND MANAGEMENT AB added 769,423 shares (+390.5%) to their portfolio in Q2 2026, for an estimated $2,315,963
- BANK OF AMERICA CORP /DE/ removed 571,044 shares (-97.1%) from their portfolio in Q1 2026, for an estimated $833,724
- JANE STREET GROUP, LLC removed 481,551 shares (-61.3%) from their portfolio in Q1 2026, for an estimated $703,064
- JACOBS LEVY EQUITY MANAGEMENT, INC added 460,997 shares (+inf%) to their portfolio in Q1 2026, for an estimated $673,055
- MILLENNIUM MANAGEMENT LLC removed 345,482 shares (-46.5%) from their portfolio in Q1 2026, for an estimated $504,403
- EXODUSPOINT CAPITAL MANAGEMENT, LP removed 317,769 shares (-100.0%) from their portfolio in Q1 2026, for an estimated $463,942
- LAURION CAPITAL MANAGEMENT LP added 200,854 shares (+4.2%) to their portfolio in Q1 2026, for an estimated $293,246
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.
