LENZ Therapeutics grants Everest Medicines rights to develop and commercialize VIZZ for presbyopia in Greater China.
Quiver AI Summary
LENZ Therapeutics, Inc. announced that Everest Medicines has entered into an Asset Purchase Agreement with Corxel Pharmaceuticals to acquire the rights to develop and commercialize VIZZ® (aceclidine ophthalmic solution) 1.44% for presbyopia in Greater China, including mainland China, Hong Kong, Macao, and Taiwan. The New Drug Application for VIZZ in China was submitted in September 2025, with expected approval in Q1 2027. As part of the agreement, LENZ stands to receive up to $85 million in regulatory and sales milestones, along with royalties from net sales in the region. Everest Medicines views this acquisition as a step forward in enhancing its ophthalmic portfolio and aims to provide a non-invasive treatment option for the growing presbyopia patient population. LENZ, focused on global commercialization of VIZZ, looks forward to collaborating with Everest as they navigate the path toward regulatory approval and launch in China.
Potential Positives
- LENZ Therapeutics has entered into an agreement with Everest Medicines for the development, manufacturing, and commercialization of VIZZ® in Greater China, expanding its market reach significantly.
- The company is eligible to receive up to $85 million in regulatory and sales milestones, providing a substantial financial incentive.
- Everest Medicines' acquisition of LNZ100 signifies confidence in the product's potential within the presbyopia treatment market, a condition affecting approximately 1.8 billion people globally.
Potential Negatives
- The announcement indicates that LENZ has licensed VIZZ's development rights to Everest Medicines in Greater China, potentially diminishing its control over a significant market for its product.
- The press release highlights reliance on Everest Medicines for the commercialization of VIZZ in a crucial region, which could pose challenges if Everest fails to execute effectively.
- The future success of LENZ's product in China is uncertain, as it is contingent on regulatory approval and market reception, introducing potential risks to revenue expectations.
FAQ
What is VIZZ® and what condition does it treat?
VIZZ® is an aceclidine ophthalmic solution for treating presbyopia, the age-related loss of near vision.
Who is acquiring the rights to VIZZ® in Greater China?
Everest Medicines has entered into an Asset Purchase Agreement to acquire the rights to VIZZ® in Greater China.
When was the New Drug Application for LNZ100 submitted in China?
The NDA for LNZ100 was submitted to the CDE in September 2025, with approval expected in Q1 2027.
How much could LENZ Therapeutics receive from the agreement with Everest?
LENZ is eligible to receive up to $85 million in regulatory and sales milestones, plus tiered royalties on net sales.
What therapeutic areas does Everest Medicines focus on?
Everest Medicines focuses on ophthalmology, cardiovascular, kidney, metabolic, autoimmune, and critical care therapeutic areas.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$LENZ Insider Trading Activity
$LENZ insiders have traded $LENZ stock on the open market 3 times in the past 6 months. Of those trades, 3 have been purchases and 0 have been sales.
Here’s a breakdown of recent trading of $LENZ stock by insiders over the last 6 months:
- EVERT B. SCHIMMELPENNINK (President, CEO and Secretary) purchased 28,089 shares for an estimated $251,410
- DANIEL R. CHEVALLARD (Chief Financial Officer) purchased 7,500 shares for an estimated $64,275
- JEFFREY P. GEORGE purchased 5,592 shares for an estimated $49,890
To track insider transactions, check out Quiver Quantitative's insider trading dashboard. You can access data on insider stock transactions through the Quiver Quantitative API insider transaction endpoint.
$LENZ Hedge Fund Activity
We have seen 93 institutional investors add shares of $LENZ stock to their portfolio, and 112 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- UBS GROUP AG removed 1,414,749 shares (-90.0%) from their portfolio in Q1 2026, for an estimated $12,944,953
- PARADIGM BIOCAPITAL ADVISORS LP removed 1,073,461 shares (-100.0%) from their portfolio in Q4 2025, for an estimated $17,175,376
- SQUAREPOINT OPS LLC added 1,014,601 shares (+206.3%) to their portfolio in Q1 2026, for an estimated $9,283,599
- PRICE T ROWE ASSOCIATES INC /MD/ removed 983,921 shares (-96.1%) from their portfolio in Q1 2026, for an estimated $9,002,877
- RTW INVESTMENTS, LP removed 863,389 shares (-100.0%) from their portfolio in Q4 2025, for an estimated $13,814,224
- FIRST LIGHT ASSET MANAGEMENT, LLC removed 693,044 shares (-100.0%) from their portfolio in Q4 2025, for an estimated $11,088,704
- ABERDEEN GROUP PLC added 666,729 shares (+136.2%) to their portfolio in Q1 2026, for an estimated $6,100,570
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.
$LENZ Price Targets
Multiple analysts have issued price targets for $LENZ recently. We have seen 4 analysts offer price targets for $LENZ in the last 6 months, with a median target of $24.5.
Here are some recent targets:
- Yigal Nochomovitz from Citigroup set a target price of $20.0 on 05/13/2026
- Biren Amin from Piper Sandler set a target price of $12.0 on 05/12/2026
- Matthew Caufield from HC Wainwright & Co. set a target price of $38.0 on 05/12/2026
- Jason Gerberry from B of A Securities set a target price of $29.0 on 03/25/2026
Full Release
SAN DIEGO, June 07, 2026 (GLOBE NEWSWIRE) -- LENZ Therapeutics, Inc. (Nasdaq: LENZ, “LENZ” or the “Company”), a pharmaceutical company focused on the commercialization of VIZZ ® (aceclidine ophthalmic solution) 1.44%, the first and only aceclidine-based eye drop for the treatment of presbyopia, today announced that Everest Medicines (HKEX1952, or “Everest”), has entered into an Asset Purchase Agreement with Corxel Pharmaceuticals (“CORXEL”) to acquire the rights to develop, manufacture, and commercialize VIZZ (LNZ100) in Greater China, including Chinese mainland, Hong Kong SAR, Macao SAR, and Taiwan region.
Everest Medicines is a biopharmaceutical company focused on discovering, developing, manufacturing and commercializing innovative pharmaceutical products that address critical unmet medical needs for patients in global markets, with therapeutic areas of focus including ophthalmology, CKM (cardiovascular, kidney, and metabolic), autoimmune and critical care.
The New Drug Application (NDA) for LNZ100 in China was submitted to the Center for Drug Evaluation (CDE) of the National Medical Products Administration (NMPA) of the People’s Republic of China (PRC) in September 2025, with approval anticipated in Q1 2027. As part of this agreement, Everest will be assigned and transferred the rights and obligations under the LENZ License Agreement entered into by CORXEL in April 2022 and certain related ancillary agreements. LENZ is eligible to receive up to $85.0 million in remaining regulatory and sales milestones, as well as tiered mid single-digit to low double-digit royalties on net sales in Greater China. LENZ is also now eligible to receive additional payments in connection with the execution of the agreement between CORXEL and Everest.
"The acquisition of LNZ100 represents an important step in advancing Everest’s strategic focus in ophthalmology. LNZ100 is a differentiated asset with meaningful clinical value and strong commercial potential in the treatment of presbyopia,” said Yifang Wu, Chairman of the Board of Everest Medicines. “As the presbyopia patient population continues to grow, significant unmet needs remain in non-invasive treatment options. We believe LNZ100 has the potential to offer patients a novel, non-invasive therapeutic option and to further broaden the landscape of innovative ophthalmic treatments. The product has already been approved in the United States and is currently under regulatory review in China. We will continue to advance its development and commercialization to make this therapy accessible to presbyopia patients."
“We thank the CORXEL team for their partnership in the clinical execution and regulatory stewardship of LNZ100 in China”, said Eef Schimmelpennink, President and Chief Executive Officer of LENZ Therapeutics. “We look forward to collaborating with Everest as we approach regulatory approval and commercial launch in China, providing a transformative new treatment option for millions of adults living with presbyopia.”
About LENZ Therapeutics
LENZ Therapeutics is a pharmaceutical company focused on the commercialization of VIZZ ® (aceclidine ophthalmic solution) 1.44%, the first and only FDA-approved aceclidine-based eye drop for the treatment of presbyopia, a condition impacting an estimated 1.8 billion people globally and 128 million people in the United States. LENZ is commercializing VIZZ in the United States and continues to establish licensing partnerships internationally to provide access to VIZZ globally. LENZ is headquartered in San Diego, California. For more information, visit www.VIZZ.com and www.lenz-tx.com .
About Everest Medicines
Everest Medicines is a biopharmaceutical company focused on discovering, developing, manufacturing and commercializing innovative pharmaceutical products that address critical unmet medical needs for patients in global markets. The management team of Everest Medicines has deep expertise and an extensive track record both in China and with leading global pharmaceutical companies. The Company’s therapeutic areas of focus include CKM (cardiovascular, kidney, and metabolic), autoimmune, ophthalmology and critical care. Everest Medicines has developed a fully integrated commercialization platform that combines omnichannel commercial capabilities with end-to-end product lifecycle management. Leveraging its proprietary mRNA platform, the Company is advancing its existing pipeline, including mRNA in vivo CAR-T and mRNA cancer vaccines, while selectively expanding into additional high-value therapeutic areas with blockbuster potential, and accelerating its global expansion. For more information, please visit the Company’s website: www.everestmedicines.com .
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of United States federal securities laws. You can identify forward-looking statements by words such as “may,” “will,” “could,” “can,” “would,” “should,” “expect,” “intend,” “plan,” “anticipate,” “believe,” “estimate,” “predict,” “project,” “potential,” “poised,” “continue,” “ongoing” or the negative of these terms or other comparable terminology, but not all forward-looking statements will contain these words. Forward-looking statements in this press release include, but are not limited to, statements regarding the potential of approval of LNZ100 in Greater China; and plans and expectations regarding the commercialization of LNZ100 in China, if approved. These statements are based on numerous assumptions concerning LENZ, VIZZ, target markets and regulatory agencies and involve substantial risks, uncertainties and other factors that could cause actual results to differ materially from those projected, expressed or implied by these forward-looking statements, including risks related to regulatory approvals, market conditions, and those risk factors described in the section titled “Risk Factors” in our Quarterly Report on Form 10-Q filed for the quarter ended March 31, 2026 and our subsequent filings with the Securities and Exchange Commission. We cannot assure you that the forward-looking statements in this press release or the assumptions upon which they are based will prove to be accurate. The forward-looking statements in this press release are made as of the date of this press release. Except as otherwise required by applicable law, LENZ disclaims any duty to update any forward-looking statements. You should, therefore, not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this press release.
Contact:
Dan Chevallard
LENZ Therapeutics
[email protected]