Esperion partners with HLS Therapeutics for exclusive commercialization rights of heart disease products in Canada, receiving upfront payments and royalties.
Quiver AI Summary
Esperion Therapeutics has announced a license and distribution agreement with HLS Therapeutics for the exclusive rights to commercialize its cholesterol-lowering medications NEXLETOL and NEXLIZET in Canada. This partnership aims to enhance access to these therapies for the 2.6 million Canadians living with diagnosed heart disease, which is a leading cause of mortality in the country. Under the terms of the agreement, Esperion will receive an upfront payment, potential milestone payments of up to $5 million, and tiered royalties on sales. HLS will manage the commercialization, including marketing and reimbursement efforts, while Esperion will supply the products. Both companies express enthusiasm about the collaboration, highlighting their commitment to expanding access to innovative treatments for cardiovascular disease.
Potential Positives
- Esperion has secured a license and distribution agreement with HLS Therapeutics, which includes an upfront payment and potential milestone payments of up to approximately $5 million, enhancing its financial position.
- This partnership allows Esperion to expand access to its bempedoic acid products, addressing the needs of approximately 2.6 million Canadians living with diagnosed heart disease, emphasizing the company's commitment to public health.
- The collaboration with HLS Therapeutics enhances Esperion's commercialization efforts, as HLS will handle marketing and reimbursement in Canada, allowing Esperion to focus on product supply and development.
Potential Negatives
- Esperion will be responsible for supplying finished products to HLS Therapeutics at a profitable transfer price, which may strain the company's resources or profitability.
- The agreement grants exclusive commercialization rights to HLS Therapeutics, potentially limiting Esperion's control over its product sales and marketing strategies in Canada.
- There is no specific mention of how the partnership will enhance Esperion's overall market position or financial stability, implying possible uncertainties in revenue generation from this deal.
FAQ
What is Esperion's recent agreement with HLS Therapeutics?
Esperion has entered into a license and distribution agreement granting HLS exclusive rights to commercialize NEXLETOL and NEXLIZET in Canada.
What payments will Esperion receive from HLS Therapeutics?
Esperion will receive an upfront payment, milestone payments of up to $5 million, and tiered royalties on product sales.
How many Canadians are affected by heart disease?
Approximately 2.6 million Canadians aged 20 and over are living with diagnosed heart disease, according to the Government of Canada.
What are NEXLETOL and NEXLIZET?
NEXLETOL and NEXLIZET are commercial brand names for bempedoic acid and bempedoic acid combined with ezetimibe, respectively.
What is Esperion's focus as a biopharmaceutical company?
Esperion focuses on developing innovative oral therapies for patients at risk for cardiovascular disease, specifically addressing unmet medical needs.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$ESPR Insider Trading Activity
$ESPR insiders have traded $ESPR stock on the open market 13 times in the past 6 months. Of those trades, 0 have been purchases and 13 have been sales.
Here’s a breakdown of recent trading of $ESPR stock by insiders over the last 6 months:
- SHELDON L. KOENIG (President and CEO) has made 0 purchases and 2 sales selling 25,494 shares for an estimated $50,316.
- BENJAMIN HALLADAY (Chief Financial Officer) has made 0 purchases and 5 sales selling 6,808 shares for an estimated $13,156.
- ERIC WARREN (Chief Commercial Officer) has made 0 purchases and 6 sales selling 5,334 shares for an estimated $10,300.
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$ESPR Hedge Fund Activity
We have seen 74 institutional investors add shares of $ESPR stock to their portfolio, and 87 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- MORGAN STANLEY added 3,663,178 shares (+138.4%) to their portfolio in Q4 2024, for an estimated $8,058,991
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$ESPR Analyst Ratings
Wall Street analysts have issued reports on $ESPR in the last several months. We have seen 1 firms issue buy ratings on the stock, and 0 firms issue sell ratings.
Here are some recent analyst ratings:
- Cantor Fitzgerald issued a "Overweight" rating on 12/17/2024
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Full Release
– Esperion to Receive an Upfront Payment, Near-Term Milestones and Tiered Royalties on Product Sales –
– Further Expands Global Access to Bempedoic Acid Products and Provides Opportunity to Bring Innovative Preventative Therapy to 2.6 million Canadians Living with Diagnosed Heart Disease –
ANN ARBOR, Mich., May 08, 2025 (GLOBE NEWSWIRE) -- Esperion Therapeutics (NASDAQ: ESPR) today announced it has entered into a license and distribution agreement with HLS Therapeutics (TSX:HLS) for the exclusive rights to commercialize NEXLETOL * and NEXLIZET * in Canada. Under the terms of the agreement, Esperion will receive an upfront payment, near-term milestone and tiered royalties on product sales. Esperion will be responsible for supplying finished product to HLS Therapeutics at a profitable transfer price.
According to the Government of Canada, approximately one in 12 Canadian adults aged 20 and over, which represents 2.6 million people, are living with diagnosed heart disease. It is the second leading cause of death in Canada, with approximately 14 Canadian adults aged 20 and over dying every hour due to diagnosed heart disease.
“We are excited about the opportunity to partner with Esperion to bring these innovative treatments to the many Canadians suffering from, or at risk of, cardiovascular disease,” said Craig Millian, CEO at HLS.
“We’re thrilled to collaborate with HLS to expand the reach of our therapies to patients throughout Canada who are at risk of cardiovascular disease,” said Sheldon Koenig, President and CEO of Esperion. “This collaboration underscores and supports our commitment to expand global access to our potentially life-saving therapies.”
Details of the Agreement and Financial Terms
Under the terms of the license and distribution agreement, Esperion will grant HLS Therapeutics exclusive commercialization rights to NEXLETOL and NEXLIZET in Canada. HLS Therapeutics will be responsible for commercialization, including reimbursement and marketing.
Esperion will receive an upfront payment and be eligible for milestone payments of up to approximately $5 million along with tiered royalties on product sales.
* NEXLETOL ® (bempedoic acid) and NEXLIZET ® (bempedoic acid and ezetimibe) are the commercial brand names in the U.S. The brand names in Canada to be confirmed upon approval by Health Canada.
About HLS Therapeutics
Formed in 2015, HLS is a pharmaceutical company focused on the acquisition and commercialization of late-stage development, commercial stage promoted and established branded pharmaceutical products in the North American markets. HLS’s focus is on products that address unmet needs in the treatment of psychiatric disorders and cardiovascular disease. HLS’s management team is composed of seasoned pharmaceutical executives with a strong track record of success in these therapeutic areas and at managing products in each of these lifecycle stages. For more information visit:
www.hlstherapeutics.com
.
About Esperion Therapeutics
Esperion Therapeutics, Inc. is a commercial stage biopharmaceutical company focused on bringing new medicines to market that address unmet needs of patients and healthcare professionals. The Company developed and is commercializing the only U.S. Food and Drug Administration (FDA) approved oral, once-daily, non-statin medicines for patients who are at risk for cardiovascular disease and are struggling with elevated low density lipoprotein cholesterol (LDL-C). These medications are supported by the nearly 14,000 patient CLEAR Cardiovascular Outcomes Trial. Esperion continues to build on its success with its next generation program which is focused on developing ATP citrate lyase inhibitors (ACLYi). New insights into the structure and function of ACLYi fully enables rational drug design and the opportunity to develop highly potent and specific inhibitors with allosteric mechanisms.
Esperion continues to evolve into a leading global biopharmaceutical company through commercial execution, international partnerships and collaborations and advancement of its pre-clinical pipeline. For more information, visit esperion.com and follow Esperion on LinkedIn and X .
Forward-Looking Statements
This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding marketing strategy and commercialization plans, current and planned operational expenses, future operations, commercial products, clinical development, including the timing, designs and plans for the CLEAR Outcomes study and its results, plans for potential future product candidates, financial condition and outlook, including expected cash runway, and other statements containing the words “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “predict,” “project,” “suggest,” “target,” “potential,” “will,” “would,” “could,” “should,” “continue,” and similar expressions. Any express or implied statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Forward-looking statements involve risks and uncertainties that could cause Esperion’s actual results to differ significantly from those projected, including, without limitation, the net sales, profitability, and growth of Esperion’s commercial products, clinical activities and results, supply chain, commercial development and launch plans, the outcomes and anticipated benefits of legal proceedings and settlements, and the risks detailed in Esperion’s filings with the Securities and Exchange Commission. Any forward-looking statements contained in this press release speak only as of the date hereof, and Esperion disclaims any obligation or undertaking to update or revise any forward-looking statements contained in this press release, other than to the extent required by law.
Esperion Contact Information:
Investors:
Alina Venezia
[email protected]
(734) 887-3903
Media:
Tiffany Aldrich
[email protected]
(616) 443-8438