Xilio Therapeutics appoints Akintunde Bello, Ph.D., to its board, enhancing expertise in oncology and immuno-oncology developments.
Quiver AI Summary
Xilio Therapeutics, Inc. announced the appointment of Dr. Akintunde Bello to its board of directors. Dr. Bello, who has over 25 years of experience in oncology research and development, will contribute valuable expertise as Xilio advances its innovative tumor-activated immuno-oncology therapies, including its lead candidate XTX501. Paul Clancy, chair of the board, expressed enthusiasm for Dr. Bello's arrival, noting his impressive background with cancer immunotherapies at Bristol Myers Squibb and Pfizer. Dr. Bello emphasized the potential of Xilio's approach to improve cancer treatment outcomes while minimizing side effects.
Potential Positives
- Appointment of Akintunde Bello, Ph.D., to the board of directors enhances Xilio's leadership with his extensive experience in oncology drug development and immunotherapy.
- Dr. Bello's prior roles at Bristol Myers Squibb and Pfizer bring valuable expertise that can help advance Xilio’s tumor-activated immuno-oncology therapies.
- The press release highlights Xilio's commitment to improving cancer treatment outcomes while minimizing side effects, aligning with current healthcare needs.
Potential Negatives
- The press release heavily discusses the appointment of a new board member, which may indicate the company is seeking expertise due to current challenges or uncertainties in their drug development pipeline.
- There are multiple cautionary statements regarding risks and uncertainties that could impact the company's clinical trials and product development, highlighting potential instability or issues ahead.
- The need for ongoing collaborations with other major pharmaceutical companies like Roche, Gilead, and AbbVie is emphasized, suggesting potential dependencies that could affect Xilio's independence and strategic direction.
FAQ
Who is Akintunde Bello, Ph.D.?
Akintunde Bello, Ph.D., is a new member of Xilio Therapeutics' board with over 25 years of experience in oncology drug development.
What role will Dr. Bello play at Xilio Therapeutics?
Dr. Bello will contribute his expertise to advance Xilio's innovative tumor-activated immuno-oncology therapies.
What therapies is Xilio Therapeutics currently developing?
Xilio is developing tumor-activated immuno-oncology therapies, including the bi-specific XTX501 and other novel T cell engager programs.
What is the focus of Xilio Therapeutics' research?
Xilio focuses on creating therapies that improve cancer outcomes while minimizing systemic side effects through tumor activation.
How can I learn more about Xilio Therapeutics?
For more information, visit Xilio's website at www.xiliotx.com or follow them on LinkedIn.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$XLO Insider Trading Activity
$XLO insiders have traded $XLO stock on the open market 1 times in the past 6 months. Of those trades, 1 have been purchases and 0 have been sales.
Here’s a breakdown of recent trading of $XLO stock by insiders over the last 6 months:
- SCIENCES, INC. GILEAD purchased 1,759,978 shares for an estimated $1,830,377
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$XLO Hedge Fund Activity
We have seen 14 institutional investors add shares of $XLO stock to their portfolio, and 15 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- ROCK SPRINGS CAPITAL MANAGEMENT LP removed 3,003,259 shares (-100.0%) from their portfolio in Q1 2025, for an estimated $2,175,560
- FMR LLC removed 511,818 shares (-36.7%) from their portfolio in Q1 2025, for an estimated $370,760
- VANGUARD GROUP INC added 233,185 shares (+25.8%) to their portfolio in Q1 2025, for an estimated $168,919
- FIL LTD removed 218,705 shares (-100.0%) from their portfolio in Q1 2025, for an estimated $158,429
- MORGAN STANLEY added 154,479 shares (+15.4%) to their portfolio in Q1 2025, for an estimated $111,904
- AVANTAX PLANNING PARTNERS, INC. added 150,399 shares (+inf%) to their portfolio in Q1 2025, for an estimated $108,949
- RENAISSANCE TECHNOLOGIES LLC removed 118,917 shares (-40.1%) from their portfolio in Q1 2025, for an estimated $86,143
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard.
Full Release
WALTHAM, Mass., June 10, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced the appointment of Akintunde (Tunde) Bello, Ph.D., to the company’s board of directors.
“Tunde is an accomplished leader with a strong track record of successfully developing novel therapies across a broad range of therapeutic areas, including several important cancer immunotherapies for anti-CTLA-4, PD-1 and T-cell engager through all stages of development, and I am thrilled to welcome him to the board,” said Paul Clancy, chair of the board of directors of Xilio Therapeutics. “With over 25 years of experience in oncology research and development, focused on translational medicine and clinical pharmacology at BMS and Pfizer, we look forward to benefitting from Tunde’s extensive expertise as we advance toward the clinic with XTX501, our masked PD-1/IL-2 bi-specific, and our bi-specific and tri-specific masked T cell engager programs.”
“Xilio’s innovative approach to developing tumor-activated immuno-oncology therapies presents an exciting opportunity to advance novel molecules, which hold the potential to overcome the limitations of current cancer treatments,” said Dr. Bello. “I am honored to join Xilio’s board of directors at this important time and look forward to contributing to Xilio’s efforts to meaningfully improve outcomes for patients while minimizing systemic toxicities.”
Akintunde Bello, Ph.D.
Dr. Bello brings more than 25 years of oncology drug development and leadership experience to Xilio, with deep expertise in early translational medicine and clinical pharmacology across complex biologics and immunotherapies, including anti-CTLA-4 and PD-1 checkpoint inhibitors, T cell engagers and tumor-selective molecules. He most recently served as senior vice president, head of clinical pharmacology, pharmacometrics and bioanalysis at Bristol Myers Squibb Company (BMS) until his retirement in 2025. While at BMS, Dr. Bello oversaw clinical pharmacology and pharmacometrics across multiple therapeutic areas. Prior to BMS, Dr. Bello spent more than a decade with Pfizer Inc. (Pfizer), where he was responsible for overseeing clinical pharmacology for Pfizer’s late-stage oncology development programs. Dr. Bello received a B.Sc. in biomedical sciences from Portsmouth Polytechnic, an M.Sc. in instrumentation and analytical science from University of Manchester and a Ph.D. in pharmaceutical sciences from King’s College, University of London.
About Xilio Therapeutics
Xilio Therapeutics is a clinical-stage biotechnology company discovering and developing tumor-activated, or masked, immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. The company is leveraging its proprietary platform to advance a pipeline of novel, tumor-activated I-O molecules that are designed to optimize the therapeutic index by localizing anti-tumor activity within the tumor microenvironment. Learn more by visiting www.xiliotx.com and follow us on LinkedIn ( Xilio Therapeutics, Inc ).
Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, statements regarding achievement of key milestones; and the potential benefits of any of Xilio’s current or future product candidates in treating patients; and Xilio’s strategy, goals, business plans and focus. The words “aim,” “may,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “seek,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management’s current expectations and beliefs and are subject to a number of important risks, uncertainties and other factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release, including, without limitation, general market conditions; risks and uncertainties related to ongoing and planned research and development activities, including initiating, conducting or completing preclinical studies and clinical trials and the timing and results of such preclinical studies or clinical trials; the delay of any current or planned preclinical studies or clinical trials or the development of Xilio’s current or future product candidates; Xilio’s ability to obtain and maintain sufficient preclinical and clinical supply of current or future product candidates; Xilio’s advancement of multiple early-stage immune cell engager programs; interim or preliminary preclinical or clinical data or results, which may not be replicated in or predictive of future preclinical or clinical data or results; Xilio’s ability to successfully demonstrate the safety and efficacy of its product candidates and gain approval of its product candidates on a timely basis, if at all; results from preclinical studies or clinical trials for Xilio’s product candidates, which may not support further development of such product candidates; actions of regulatory agencies, which may affect the initiation, timing and progress of current or future clinical trials; Xilio’s ability to obtain, maintain and enforce patent and other intellectual property protection for current or future product candidates; Xilio’s ability to obtain and maintain sufficient cash resources to fund its operations; the impact of international trade policies on Xilio’s business, including U.S. and China trade policies; Xilio’s ability to maintain its clinical trial collaboration with Roche to develop vilastobart in combination with atezolizumab; and Xilio’s ability to maintain its collaboration and partnership agreements with Gilead and AbbVie. These and other risks and uncertainties are described in greater detail in the sections entitled “Risk Factor Summary” and “Risk Factors” in Xilio’s filings with the U.S. Securities and Exchange Commission (SEC), including Xilio’s most recent Quarterly Report on Form 10-Q and any other filings that Xilio has made or may make with the SEC in the future. Any forward-looking statements contained in this press release represent Xilio’s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date. Except as required by law, Xilio explicitly disclaims any obligation to update any forward-looking statements.
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Investor and Media Contact
Scott Young
Vice President, Investor Relations and Corporate Communications
[email protected]