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Shattuck Labs Reports $15.2 Million Q2 Loss and 2029 Cash Runway

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Shattuck Labs (STTK) reported second-quarter 2026 financial results and recent business updates, including Phase 1 clinical trial results for SL-325 and plans to start the RECEPTIVE-CD1 Phase 2b trial in Crohn’s disease in the third quarter of 2026.

The company reported $208.3 million in cash, cash equivalents and short-term investments as of June 30, 2026, which it expects to fund operations into 2029.

  • Net loss was $15.2 million for the quarter ended June 30, 2026, or $0.12 per basic and diluted share.
  • Revenue was $0 for the second quarter of 2026.
  • R&D expenses were $11.7 million, compared with $8.7 million a year earlier.
  • G&A expenses were $4.5 million, compared with $4.4 million a year earlier.
  • SL-325 Phase 1 results showed a favorable safety profile, 3.7% antidrug antibody rate and durable DR3 blockade of TL1A binding.
  • The SL-325 RECEPTIVE-CD1 Phase 2b Crohn’s disease trial is expected to begin in the third quarter of 2026, with primary endpoint data expected in the first half of 2028.
  • Shattuck announced SL-846, a DR3 x IL-23 receptor blocking bispecific antibody, with initial Phase 1 clinical data expected in 2027.
  • The company completed an underwritten public offering with approximately $86.2 million in gross proceeds, and warrant exercises generated approximately $57.1 million in gross proceeds.

$STTK Insider Trading Activity

STTK Insider Trades

$STTK insiders have traded $STTK stock on the open market 7 times in the past 6 months. Of those trades, 1 have been purchases and 6 have been sales.

Here’s a breakdown of recent trading of $STTK stock by insiders over the last 6 months:

  • ARUNDATHY N. PANDITE (Chief Medical Officer) has made 0 purchases and 2 sales selling 60,000 shares for an estimated $408,600.
  • CLAY B SIEGALL purchased 62,500 shares for an estimated $250,000
  • ABHINAV A. SHUKLA (Chief Technical Officer) has made 0 purchases and 4 sales selling 25,907 shares for an estimated $183,249.

To track insider transactions, check out Quiver Quantitative's insider trading dashboard. You can access data on insider stock transactions through the Quiver Quantitative API insider transaction endpoint.

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$STTK Hedge Fund Activity

We have seen 57 institutional investors add shares of $STTK stock to their portfolio, and 22 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.

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