Kyverna Therapeutics will host a conference call on December 15, 2025, to present Phase 2 trial results for KYV-101.
Quiver AI Summary
Kyverna Therapeutics, Inc. announced a live webcast and conference call scheduled for December 15, 2025, at 8:00 am ET to discuss the topline results of the Phase 2 KYSA-8 clinical trial for KYV-101, a CAR T-cell therapy being evaluated for stiff person syndrome. Participants must register to join the call or can access the information via a live webcast, with archived materials available later on the company’s website. KYV-101 aims to provide deep B-cell depletion and immune system reset for patients with autoimmune diseases. Kyverna, focusing on developing cell therapies for autoimmune conditions, is also advancing other clinical trials for diseases such as myasthenia gravis, lupus nephritis, multiple sclerosis, and rheumatoid arthritis.
Potential Positives
- Kyverna Therapeutics is set to present topline results from the Phase 2 KYSA-8 clinical trial, which could indicate progress in the development of its lead therapy, KYV-101, for stiff person syndrome.
- The company is advancing through late-stage clinical development with multiple trials, indicating a strong pipeline and potential future growth in the autoimmune disease sector.
- KYV-101 has demonstrated potential for deep B-cell depletion and immune system reset, which could lead to significant advancements in treatment for B-cell-driven autoimmune diseases.
Potential Negatives
- The press release highlights the company's reliance on forward-looking statements, indicating uncertainty about future results and outcomes, which may concern investors regarding the stability and predictability of their clinical developments.
- Kyverna Therapeutics is in a clinical-stage, suggesting they have not yet achieved market approval for their lead product, indicating the potential for financial instability and ongoing operational risks.
- The mention of various important factors that could lead to actual results differing materially from expectations underscores the potential volatility of the company's stock and investor sentiment.
FAQ
When is the Kyverna Therapeutics conference call?
The conference call will be hosted on December 15, 2025, at 8:00 am ET.
How can I register for the conference call?
Participants must register at the provided URL to receive a dial-in number and PIN for the call.
What are the topline results from the KYSA-8 trial?
The topline results from the registrational Phase 2 KYSA-8 trial will be reviewed during the conference call.
What is KYV-101 developed for?
KYV-101 is designed for treating stiff person syndrome and other B-cell-driven autoimmune diseases.
Where can I find the archived conference call?
The archived replay of the call will be available on Kyverna's Investor Relations webpage after the event.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$KYTX Hedge Fund Activity
We have seen 30 institutional investors add shares of $KYTX stock to their portfolio, and 65 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- NOVO HOLDINGS A/S removed 1,850,000 shares (-100.0%) from their portfolio in Q2 2025, for an estimated $5,679,500
- PRICE T ROWE ASSOCIATES INC /MD/ removed 318,302 shares (-17.4%) from their portfolio in Q3 2025, for an estimated $1,909,812
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- SUSQUEHANNA INTERNATIONAL GROUP, LLP added 130,421 shares (+180.5%) to their portfolio in Q3 2025, for an estimated $782,526
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard.
$KYTX Analyst Ratings
Wall Street analysts have issued reports on $KYTX in the last several months. We have seen 3 firms issue buy ratings on the stock, and 0 firms issue sell ratings.
Here are some recent analyst ratings:
- Wells Fargo issued a "Overweight" rating on 10/30/2025
- HC Wainwright & Co. issued a "Buy" rating on 10/27/2025
- William Blair issued a "Outperform" rating on 08/20/2025
To track analyst ratings and price targets for $KYTX, check out Quiver Quantitative's $KYTX forecast page.
$KYTX Price Targets
Multiple analysts have issued price targets for $KYTX recently. We have seen 3 analysts offer price targets for $KYTX in the last 6 months, with a median target of $25.0.
Here are some recent targets:
- Michael Ulz from Morgan Stanley set a target price of $25.0 on 12/04/2025
- Derek Archila from Wells Fargo set a target price of $31.0 on 10/30/2025
- Mitchell S. Kapoor from HC Wainwright & Co. set a target price of $20.0 on 10/27/2025
Full Release
EMERYVILLE, Calif., Dec. 14, 2025 (GLOBE NEWSWIRE) -- Kyverna Therapeutics, Inc. (Nasdaq: KYTX), a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases, announced it will host a live webcast and conference call on Monday, December 15, 2025 at 8:00 am ET to review topline results from the registrational Phase 2 KYSA-8 clinical trial evaluating KYV-101 in stiff person syndrome (SPS).
Conference Call Details
Participants will need to register at the below-noted URL in order to listen and participate in the call. Once registered, participants will receive a dial-in phone number and unique PIN number which will be needed to join the call. The call can also be accessed via live webcast. The webcast and supporting presentation materials will be available on the "Events & Presentations" section of Kyverna's Investor Relations webpage at ir.kyvernatx.com . An archived replay will also be available on the website.
Dial-In Registration Link:
Conference Call Registration
Webcast Link:
Kyverna Topline Results for SPS Conference Call
About KYV-101
KYV-101 is a fully human, autologous, CD19 CAR T-cell therapy with CD28 co-stimulation, designed for potency and tolerability, which is under investigation for B-cell-driven autoimmune diseases. With a single administration, KYV-101 has potential to achieve deep B-cell depletion and immune system reset to deliver durable drug-free, disease-free remission in autoimmune diseases.
About Kyverna Therapeutics
Kyverna Therapeutics, Inc. (Nasdaq: KYTX) is a clinical-stage biopharmaceutical company focused on liberating patients through the curative potential of cell therapy. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through late-stage clinical development with registrational trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase 1/2 trials for patients with lupus nephritis. The Company is also harnessing other KYSA trials and investigator-initiated trials, including in multiple sclerosis and rheumatoid arthritis, to inform the next priority indications for the Company to advance into late-stage development. Additionally, its pipeline includes next-generation CAR T-cell therapies in both autologous and allogeneic formats, including efficiently expanding into broader autoimmune indications and the potential to increase patient reach with KYV-102 using its proprietary whole blood rapid manufacturing process. For more information, please visit https://kyvernatx.com .
Forward-Looking Statements
Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute “forward-looking statements.” The words, without limitation, “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these or similar identifying words. Forward-looking statements in this press release include, without limitation, those related to Kyverna’s anticipated timing for its live webcast reporting its trial data and results and the topics expected to be discussed on the webcast and Kyverna’s next priority indications. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: uncertainties related to market conditions, the possibility that results from prior clinical trials, named-patient access activities and preclinical studies may not necessarily be predictive of future results; and other factors discussed in the “Risk Factors” section of Kyverna’s most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q that Kyverna has filed or may subsequently file with the U.S. Securities and Exchange Commission. Any forward-looking statements contained in this press release are based on the current expectations of Kyverna’s management team and speak only as of the date hereof, and Kyverna specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.
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