Halozyme jumps as Q1 results, $1B buyback authorization, and new partnership updates lift sentiment

Halozyme Therapeutics, Inc. (HALO) is up 9.6% today. Here is some analysis on what might have caused this price movement.

Analysis: The move appears tied to the company’s first-quarter 2026 update, which highlighted strong year-over-year revenue and royalty growth, a newly authorized $1 billion share repurchase program, and reiterated full-year guidance. Investors also seemed to respond to recent collaboration momentum for its ENHANZE and Hypercon platforms.

Details:

Halozyme reported first-quarter 2026 total revenue of about $377 million, up roughly 42% year over year, with royalty revenue of about $241 million, up roughly 43%.

The company authorized a new share repurchase program of up to $1 billion through December 31, 2028, and said it expects to repurchase at least $400 million of shares during 2026.

Management reiterated 2026 financial guidance ranges, including total revenue of $1.71–$1.81 billion and royalty revenue of $1.13–$1.17 billion (along with reiterated non-GAAP EPS guidance).

Halozyme disclosed recent partnership activity, including a collaboration and license agreement with GSK for ENHANZE across multiple oncology targets, which could expand the long-term royalty runway if partnered programs advance.

Sources:

PR Newswire, U.S. Securities and Exchange Commission, FINVIZ

Disclaimer: This price movement analysis was generated with the help of AI. Please double-check the information provided for mistakes.

$HALO Insider Trading Activity

$HALO insiders have traded $HALO stock on the open market 36 times in the past 6 months. Of those trades, 0 have been purchases and 36 have been sales.

Here’s a breakdown of recent trading of $HALO stock by insiders over the last 6 months:

HELEN TORLEY (PRESIDENT AND CEO) has made 0 purchases and 30 sales selling 206,569 shares for an estimated $14,492,394.
CORTNEY CAUDILL (SVP, CHIEF OPERATING OFFICER) has made 0 purchases and 3 sales selling 28,857 shares for an estimated $1,955,159.
BERNADETTE CONNAUGHTON has made 0 purchases and 3 sales selling 4,454 shares for an estimated $303,011.

To track insider transactions, check out Quiver Quantitative's insider trading dashboard. You can access data on insider stock transactions through the Quiver Quantitative API insider transaction endpoint.

$HALO Hedge Fund Activity

We have seen 301 institutional investors add shares of $HALO stock to their portfolio, and 319 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC added 1,842,956 shares (+inf%) to their portfolio in Q4 2025, for an estimated $124,030,938
MACQUARIE GROUP LTD removed 1,546,185 shares (-100.0%) from their portfolio in Q4 2025, for an estimated $104,058,250
NORGES BANK added 1,039,354 shares (+120.1%) to their portfolio in Q4 2025, for an estimated $69,948,524
D. E. SHAW & CO., INC. removed 1,000,909 shares (-37.8%) from their portfolio in Q4 2025, for an estimated $67,361,175
MIZUHO MARKETS AMERICAS LLC added 926,526 shares (+270.8%) to their portfolio in Q4 2025, for an estimated $62,355,199
MORGAN STANLEY added 920,699 shares (+53.0%) to their portfolio in Q4 2025, for an estimated $61,963,042
JANE STREET GROUP, LLC removed 911,024 shares (-84.7%) from their portfolio in Q4 2025, for an estimated $61,311,915

To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.

$HALO Congressional Stock Trading

Members of Congress have traded $HALO stock 1 times in the past 6 months. Of those trades, 1 have been purchases and 0 have been sales.

Here’s a breakdown of recent trading of $HALO stock by members of Congress over the last 6 months:

REPRESENTATIVE GILBERT RAY CISNEROS, JR. purchased up to $15,000 on 03/09.

To track congressional stock trading, check out Quiver Quantitative's congressional trading dashboard. You can access data on congressional stock trades through the Quiver Quantitative API Congress trades endpoint.

$HALO Analyst Ratings

Wall Street analysts have issued reports on $HALO in the last several months. We have seen 2 firms issue buy ratings on the stock, and 0 firms issue sell ratings.

Here are some recent analyst ratings:

TD Cowen issued a "Buy" rating on 01/08/2026
HC Wainwright & Co. issued a "Buy" rating on 12/19/2025

To track analyst ratings and price targets for $HALO, check out Quiver Quantitative's $HALO forecast page.

$HALO Price Targets

Multiple analysts have issued price targets for $HALO recently. We have seen 6 analysts offer price targets for $HALO in the last 6 months, with a median target of $90.0.

Here are some recent targets:

Vikram Purohit from Morgan Stanley set a target price of $93.0 on 05/12/2026
Mitchell S. Kapoor from HC Wainwright & Co. set a target price of $95.0 on 04/29/2026
Mohit Bansal from Wells Fargo set a target price of $75.0 on 02/19/2026
Robert Wasserman from Benchmark set a target price of $90.0 on 02/19/2026
Brendan Smith from TD Cowen set a target price of $90.0 on 01/08/2026
Graig Suvannavejh from Goldman Sachs set a target price of $56.0 on 11/18/2025

This article is not financial advice. See Quiver Quantitative's disclaimers for more information. Note that there may be inaccuracies due to mistakes in ticker-mapping, and other anomalies.