AIM ImmunoTech announces discussion on Phase 1b/2 trial of Ampligen® and Imfinzi® for late-stage pancreatic cancer.
Quiver AI Summary
AIM ImmunoTech announced that CEO Tom Equels and Professor Casper H.J. van Eijck discussed the recently approved Phase 2 trial of AIM's Ampligen® (rintatolimod) combined with AstraZeneca's Imfinzi® (durvalumab) for treating late-stage pancreatic cancer during a Virtual Investor segment. The trial, named DURIPANC, is a single-center, investigator-initiated study based at Erasmus Medical Center in the Netherlands. The Erasmus MC Safety Committee approved the Phase 2 Study after finding the combination treatment generally well-tolerated with no severe adverse effects in the Phase 1 safety data. AIM ImmunoTech focuses on developing therapeutics for cancers, immune disorders, and viral diseases, and its lead drug, Ampligen®, is being investigated for various clinical applications.
Potential Positives
- The approval from the Erasmus MC Safety Committee to proceed with the Phase 2 study of Ampligen® and AstraZeneca’s Imfinzi® indicates a significant advancement in the clinical trial process for late-stage pancreatic cancer treatment.
- The Phase 1 safety data review found the combination treatment to be generally well-tolerated with no treatment-related severe adverse events, which may enhance the credibility and attractiveness of the therapy to investors and stakeholders.
- The participation of the CEO and a leading medical professional in a Virtual Investor segment demonstrates transparent communication and engagement with the investment community, potentially increasing investor confidence in the company.
Potential Negatives
- The press release contains a cautionary statement highlighting the significant risks and uncertainties associated with the clinical trial process, which may undermine investor confidence.
- Although the Phase 1 data indicated that the combination treatment was generally well-tolerated, the company cannot guarantee that Ampligen will eventually be approved as a therapy, highlighting continued uncertainty about the drug's future.
- The exploratory nature of the DURIPANC study being single-centered in the Netherlands may raise questions about the robustness and generalizability of the results.
FAQ
What is the DURIPANC clinical trial?
The DURIPANC clinical trial investigates the combination of AIM's Ampligen and AstraZeneca's Imfinzi for treating late-stage pancreatic cancer.
Who are the key participants in the DURIPANC study?
The key participants include AIM CEO Thomas K. Equels and Professor Casper H.J. van Eijck from Erasmus MC.
What recent approval was announced for the DURIPANC study?
The Erasmus MC Safety Committee approved the trial to proceed to Phase 2 after reviewing Phase 1 safety data.
What is Ampligen® and its role in the study?
Ampligen® is AIM ImmunoTech's investigational drug, used as a potential treatment in combination with Imfinzi for pancreatic cancer.
Where can I find more information about AIM ImmunoTech?
More information can be found on AIM ImmunoTech's website at aimimmuno.com and through their social media channels.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
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Full Release
Tom Equels, CEO of AIM ImmunoTech and Professor Casper H.J. van Eijck, MD, PhD, Pancreato-biliary Surgeon at Erasmus MC, discuss the Phase 1b/2 clinical trial involving AIM’s Ampligen
®
(rintatolimod) and AstraZeneca’s anti-PD-L1 immune checkpoint inhibitor Imfinzi
®
(durvalumab) in the treatment of late-stage pancreatic cancer (“DURIPANC”)
Watch the “What This Means” segment
here
OCALA, Fla., Feb. 11, 2025 (GLOBE NEWSWIRE) --
AIM ImmunoTech Inc.
(NYSE American: AIM)
(“AIM” or the “Company”) today announced that AIM CEO Thomas K. Equels and Prof. Casper H.J. van Eijck, MD, PhD, Pancreato-biliary Surgeon at the Erasmus Medical Center (“Erasmus MC”) and Coordinating Investigator for the DURIPANC study in late-stage pancreatic cancer, participated in a Virtual Investor “What This Means” segment. Access the segment
here
.
As part of the segment, Mr. Equels and Professor van Eijck discuss the
recent approval
from the Erasmus MC Safety Committee to proceed with the Phase 2 Study of Ampligen
®
and AstraZeneca’s Imfinzi as a potential combination treatment for late-stage pancreatic cancer. DURIPANC is an investigator-initiated, exploratory, open-label, single-center study in the Netherlands at Erasmus MC. The approval to proceed to Phase 2 was granted following the Safety Committee’s review of the complete Phase 1 safety data, which found the combination treatment to be generally well-tolerated with no treatment-related severe adverse events or dose-limiting toxicities.
The Virtual Investor “What this Means” segment featuring AIM ImmunoTech is now available
here
.
About AIM ImmunoTech Inc.
AIM ImmunoTech Inc. is an immuno-pharma company focused on the research and development of therapeutics to treat multiple types of cancers, immune disorders and viral diseases, including COVID-19. The Company’s lead product is a first-in-class investigational drug called Ampligen ® (rintatolimod), a dsRNA and highly selective TLR3 agonist immuno-modulator with broad spectrum activity in clinical trials for globally important cancers, viral diseases and disorders of the immune system.
For more information, please visit aimimmuno.com and connect with the Company on X , LinkedIn , and Facebook .
Cautionary Statement
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 (the “PSLRA”). Words such as “may,” “will,” “expect,” “plan,” “anticipate,” “continue,” “believe,” “potential,” “upcoming” and other variations thereon and similar expressions (as well as other words or expressions referencing future events or circumstances) are intended to identify forward-looking statements. Many of these forward-looking statements involve a number of risks and uncertainties. Data, pre-clinical success and clinical success seen to date do not guarantee that Ampligen will be approved as a therapy for pancreatic cancer. The Company urges investors to consider specifically the various risk factors identified in its most recent Form 10-K, and any risk factors or cautionary statements included in any subsequent Form 10-Q or Form 8-K, filed with the U.S. Securities and Exchange Commission. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. Among other things, for those statements, the Company claims the protection of the safe harbor for forward-looking statements contained in the PSLRA. The Company does not undertake to update any of these forward-looking statements to reflect events or circumstances that occur after the date hereof.
Investor Contact:
JTC Team, LLC
Jenene Thomas
908.824.0775
[email protected]