$SION stock is down 11% today. Here's what we see in our data.

$SION stock has now fallen 11% today, according to our price data from Polygon. There has been approximately $11,558,112 of trading volume.

Here is what we see in our data on $SION (you can track the company live on Quiver's $SION stock page):

$SION Insider Trading Activity

$SION insiders have traded $SION stock on the open market 75 times in the past 6 months. Of those trades, 0 have been purchases and 75 have been sales.

Here’s a breakdown of recent trading of $SION stock by insiders over the last 6 months:

• ADVISORS LLC ORBIMED has made 0 purchases and 14 sales selling 740,185 shares for an estimated $33,180,894.
• PETER A. THOMPSON has made 0 purchases and 14 sales selling 740,185 shares for an estimated $33,180,894.
• CAPITAL MANAGEMENT, L.P. RA has made 0 purchases and 44 sales selling 540,277 shares for an estimated $21,463,465.
• GP A, LLC TPG sold 250,000 shares for an estimated $10,000,000
• JENNIFER FITZPATRICK (Chief Legal Officer) has made 0 purchases and 2 sales selling 20,500 shares for an estimated $762,348.

To track insider transactions, check out Quiver Quantitative's insider trading dashboard.

$SION Hedge Fund Activity

We have seen 66 institutional investors add shares of $SION stock to their portfolio, and 28 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

• CITADEL ADVISORS LLC added 1,051,402 shares (+2926.8%) to their portfolio in Q4 2025, for an estimated $43,254,678
• JPMORGAN CHASE & CO removed 746,807 shares (-37.7%) from their portfolio in Q4 2025, for an estimated $30,723,639
• EVENTIDE ASSET MANAGEMENT, LLC added 639,045 shares (+inf%) to their portfolio in Q4 2025, for an estimated $26,290,311
• ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC removed 619,925 shares (-17.1%) from their portfolio in Q4 2025, for an estimated $25,503,714
• RA CAPITAL MANAGEMENT, L.P. removed 540,277 shares (-5.2%) from their portfolio in Q4 2025, for an estimated $22,226,995
• STATE STREET CORP added 453,196 shares (+188.7%) to their portfolio in Q4 2025, for an estimated $18,644,483
• BLACKROCK, INC. added 446,994 shares (+52.9%) to their portfolio in Q4 2025, for an estimated $18,389,333

To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard.

$SION Analyst Ratings

Wall Street analysts have issued reports on $SION in the last several months. We have seen 1 firms issue buy ratings on the stock, and 1 firms issue sell ratings.

Here are some recent analyst ratings:

• BTIG issued a "Buy" rating on 01/07/2026
• RBC Capital issued a "Underperform" rating on 12/01/2025

To track analyst ratings and price targets for $SION, check out Quiver Quantitative's $SION forecast page.

$SION Price Targets

Multiple analysts have issued price targets for $SION recently. We have seen 5 analysts offer price targets for $SION in the last 6 months, with a median target of $58.0.

Here are some recent targets:

• Yatin Suneja from Guggenheim set a target price of $50.0 on 03/03/2026
• Kambiz Yazdi from BTIG set a target price of $58.0 on 03/02/2026
• Jonathan Wolleben from Citizens set a target price of $63.0 on 02/24/2026
• Cory Jubinville from LifeSci Capital set a target price of $60.0 on 12/23/2025
• Brian Abrahams from RBC Capital set a target price of $24.0 on 12/01/2025

You can track data on $SION on Quiver Quantitative.

This article is not financial advice. See Quiver Quantitative's disclaimers for more information. Note that there may be inaccuracies due to mistakes in ticker-mapping, and other anomalies.