Risk Factors Dashboard

Once a year, publicly traded companies issue a comprehensive report of their business, called a 10-K. A component mandated in the 10-K is the ‘Risk Factors’ section, where companies disclose any major potential risks that they may face. This dashboard highlights all major changes and additions in new 10K reports, allowing investors to quickly identify new potential risks and opportunities.

Risk Factors - ARE

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-Changes in blue
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Item 1A. Risk factors” in
this annual report on Form 10-K. Additional information regarding risk factors that may affect us is included in “Item 7. Management’s
discussion and analysis of financial condition and results of operations” in this annual report on Form 10-K. Readers of our annual
report on Form 10-K should also read our SEC and other publicly filed documents for further discussion regarding such factors.
As used in this annual report on Form 10-K, references to the “Company,” “Alexandria,” “ARE,” “we,” “us,” and “our” refer to
Alexandria Real Estate Equities, Inc. and its consolidated subsidiaries. Alexandria®, Lighthouse Design® logo, Building the Future of
Life-Changing Innovation®, That’s What’s in Our DNA®, Labspace®, Megacampus™, Alexandria Center®, Alexandria Technology
Square®, Alexandria Technology Center®, Alexandria Innovation Center®, and Alexandria Summit® are copyrights and trademarks of
Alexandria Real Estate Equities, Inc. All other company names, trademarks, and logos referenced herein are the property of their
respective owners. The following discussion should be read in conjunction with our consolidated financial statements and notes
thereto under “Item 15. Exhibits and financial statement schedules” in this annual report on Form 10-K.
ITEM 1. BUSINESS
Overview
We are a Maryland corporation formed in October 1994 that has elected to be taxed as a REIT for federal income tax
purposes. Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a best-in-class, mission-driven life science
REIT making a positive and lasting impact on the world. With our founding in 1994, Alexandria pioneered the life science real estate
niche. Alexandria is the preeminent and longest-tenured owner, operator, and developer of collaborative Megacampus™ ecosystems
in AAA life science innovation cluster locations, including Greater Boston, the San Francisco Bay Area, San Diego, Seattle,
Maryland, Research Triangle, and New York City. As of December 31, 2025, Alexandria has a total market capitalization of
$20.75 billion and an asset base in North America that includes 35.9 million RSF of operating properties and 3.5 million RSF of
Class A/A+ properties undergoing construction.
We develop dynamic Megacampus ecosystems that enable and inspire the world’s most brilliant minds and innovative
companies to create life-changing scientific and technological innovations. We believe in the utmost professionalism, humility, and
teamwork. Our tenants include multinational pharmaceutical companies; public and private biotechnology companies; life science
product, service, and medical device companies; digital health, advanced technology, and agtech companies; academic and medical
research institutions; U.S. government research agencies; non-profit organizations; and venture capital firms. Alexandria has a
longstanding and proven track record of developing Class A/A+ properties clustered in highly dynamic and collaborative
Megacampus environments that enhance our tenants’ ability to successfully recruit and retain world-class talent and inspire
productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to transformative life science companies
through our venture capital platform. We believe our unique business model and diligent underwriting ensure a high-quality and
diverse tenant base that results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater
long-term asset value.
As of December 31, 2025, we had 340 properties in North America consisting of approximately 39.4 million RSF of
operating properties and new Class A/A+ development and redevelopment properties under construction, including 47 operating
properties and development projects that are held by consolidated real estate joint ventures and three properties that are held by
unconsolidated real estate joint ventures. The occupancy percentage of our operating properties in North America was 90.9% as of
December 31, 2025. The 10-year average occupancy percentage of our operating properties as of December 31, 2025 was 95%.
Investment-grade or publicly traded large cap tenants represented 53% of our total annual rental revenue in effect as of
December 31, 2025. Additional information regarding our consolidated and unconsolidated real estate joint ventures is included in
Item 7. Management’s discussion and analysis of financial condition and results of operations” in this annual report on Form 10-K.
For information regarding risk factors that may affect us, refer to “Item 1A. Risk factors” and “Item 7. Management’s discussion and
analysis of financial condition and results of operations” in this annual report on Form 10-K.
2
Business objective and strategies
A key element of our business strategy is our unique focus on Class A/A+ properties primarily located in collaborative
Megacampus™ ecosystems in AAA life science innovation clusters. Our Megacampus ecosystems are designed for optionality and
scalability, offering our tenants a clear path to address their growth requirements, including through our future developments and
redevelopments. Strategically located near top academic and medical research institutions and equipped with curated amenities and
services, and convenient access to transit, our Megacampus ecosystems are designed to support our tenants in attracting and retaining
top talent, which we believe is a key driver of tenant demand for our properties. Our strategy also includes drawing upon our deep,
broad, and long-standing real estate and life science industry relationships in order to retain tenants, identify and attract new and
leading tenants, and source additional real estate.
Our tenant base is broad and diverse within the life science industry. For a more detailed description of our properties and
tenants, refer to “
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