SAB Biotherapeutics will present data on SAB-142 at two upcoming congresses focused on diabetes and immunology.
Quiver AI Summary
SAB Biotherapeutics, Inc. announced the presentation of data related to its lead program, SAB-142, at two upcoming scientific congresses in June 2026. The company will deliver an oral presentation at the American Diabetes Association Scientific Sessions and a poster presentation at the Federation of Clinical Immunology Societies Annual Meeting. SAB-142 is a fully human anti-thymocyte immunoglobulin currently in clinical development as a potentially disease-modifying therapy for newly diagnosed Stage 3 type 1 diabetes (T1D) patients. The presentations aim to highlight the clinical safety and mechanisms of SAB-142, as well as its potential to change the treatment landscape for T1D. SAB Biotherapeutics is focused on using advanced genetic engineering to develop therapies for autoimmune disorders, and it is currently conducting a registrational Phase 2b clinical trial named SAFEGUARD for SAB-142, with topline data expected in the second half of 2027.
Potential Positives
- SAB Biotherapeutics, Inc. will present data at two prominent congresses in June, enhancing its visibility within the diabetes and immunology communities.
- The presentations will highlight SAB-142 as a potentially best-in-class, disease-modifying therapy for newly diagnosed Stage 3 type 1 diabetes patients, which could strengthen investor confidence and interest.
- The ongoing registrational Phase 2b SAFEGUARD study for SAB-142 demonstrates the company’s commitment to advancing its clinical programs, positioning it for potential breakthroughs in treatment options for autoimmune diseases.
Potential Negatives
- The press release heavily relies on forward-looking statements that carry inherent risks and uncertainties, potentially undermining investor confidence in the company’s ability to deliver on its promises.
- The timeline for topline data readout for the SAFEGUARD study is set for the second half of 2027, indicating a long wait for investors and stakeholders for significant results.
- There is no indication of previous results from clinical trials, which may raise concerns about the track record and success rate of the company's development programs.
FAQ
What is SAB Biotherapeutics presenting at the ADA 2026 Scientific Sessions?
SAB Biotherapeutics will present an oral presentation on SAB-142 for type 1 diabetes on June 5, 2026.
When and where is the FOCIS 2026 Annual Meeting?
The FOCIS 2026 Annual Meeting is from June 9-12, 2026, in San Francisco, CA.
What is SAB-142?
SAB-142 is a fully human anti-thymocyte immunoglobulin in development for treating type 1 diabetes and other autoimmune diseases.
What clinical trial is SAB-142 currently part of?
SAB-142 is being evaluated in the registrational Phase 2b clinical trial called SAFEGUARD.
How can I access the presentations made by SAB Biotherapeutics?
The presentations will be available on SAB Biotherapeutics' website in the Presentations section after the conferences.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$SABS Hedge Fund Activity
We have seen 58 institutional investors add shares of $SABS stock to their portfolio, and 15 decrease their positions in their most recent quarter.
Here are some of the largest recent moves:
- CALIGAN PARTNERS LP added 7,967,207 shares (+inf%) to their portfolio in Q1 2026, for an estimated $30,514,402
- PERCEPTIVE ADVISORS LLC added 5,628,533 shares (+700.8%) to their portfolio in Q1 2026, for an estimated $21,557,281
- ADAGE CAPITAL PARTNERS GP, L.L.C. added 3,405,553 shares (+inf%) to their portfolio in Q1 2026, for an estimated $13,043,267
- BALYASNY ASSET MANAGEMENT L.P. added 3,285,000 shares (+690.9%) to their portfolio in Q1 2026, for an estimated $12,581,550
- MILLENNIUM MANAGEMENT LLC added 2,708,607 shares (+835.8%) to their portfolio in Q1 2026, for an estimated $10,373,964
- BLACKSTONE INC. added 2,143,585 shares (+inf%) to their portfolio in Q4 2025, for an estimated $8,017,007
- BOOTHBAY FUND MANAGEMENT, LLC added 1,481,660 shares (+inf%) to their portfolio in Q1 2026, for an estimated $5,674,757
To track hedge funds' stock portfolios, check out Quiver Quantitative's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Quiver Quantitative API 13F endpoint.
$SABS Analyst Ratings
Wall Street analysts have issued reports on $SABS in the last several months. We have seen 1 firms issue buy ratings on the stock, and 0 firms issue sell ratings.
Here are some recent analyst ratings:
- UBS issued a "Buy" rating on 01/07/2026
To track analyst ratings and price targets for $SABS, check out Quiver Quantitative's $SABS forecast page.
$SABS Price Targets
Multiple analysts have issued price targets for $SABS recently. We have seen 7 analysts offer price targets for $SABS in the last 6 months, with a median target of $11.0.
Here are some recent targets:
- Samantha Semenkow from Citigroup set a target price of $11.0 on 05/22/2026
- Roger Song from Jefferies set a target price of $11.0 on 05/20/2026
- Emily Bodnar from HC Wainwright & Co. set a target price of $10.0 on 05/12/2026
- Seema Sheoran from Rodman & Renshaw set a target price of $13.0 on 05/11/2026
- Keay Nakae from Chardan Capital set a target price of $14.0 on 03/11/2026
- Michael Yee from UBS set a target price of $7.0 on 01/07/2026
- Yatin Suneja from Guggenheim set a target price of $15.0 on 12/19/2025
Full Release
MIAMI, May 29, 2026 (GLOBE NEWSWIRE) -- SAB Biotherapeutics, Inc. (Nasdaq: SABS ), a clinical-stage biopharmaceutical company developing a fully human anti-thymocyte immunoglobulin (hATG) for type 1 diabetes (T1D) and other autoimmune diseases, today announced that it will present data at two congresses in June. SAB BIO will present an oral presentation at the 2026 Scientific Sessions of the American Diabetes Association® (ADA) being held June 5-8, 2026, in New Orleans, LA. The Company will also present a poster presentation at the Federation of Clinical Immunology Societies (FOCIS) 2026 Annual Meeting being held June 9-12, 2026, in San Francisco, CA. Data to be presented will highlight SAB BIO’s lead program, SAB-142, a potentially best-in-class, disease-modifying, redosable immunotherapy in clinical development for newly diagnosed Stage 3 T1D patients.
“We are pleased to participate in both ADA’s 2026 Scientific Sessions and FOCIS 2026 to continue engaging with the broader diabetes and immunology communities. These forums provide an important opportunity to highlight SAB-142’s clinical and mechanistic profile and to build further understanding of the potential for this unique multi-specific modality as we advance the program through the ongoing registrational Phase 2b SAFEGUARD study,” said Alexandra Kropotova, M.D., MBA, Chief Medical Officer, SAB BIO . “We look forward to continuing to collaborate with the scientific community and to advance toward our topline data readout for SAFEGUARD in the 2H 2027.”
Oral Presentation at ADA’s 2026 Scientific Sessions:
Title
:
Clinical Safety, Pharmacokinetics, Immunogenicity, and Pharmacodynamics following Repeat Dosing of SAB-142, a Fully Human Multi-Specific Antithymocyte Globulin for New-Onset Type 1 Diabetes
Session:
Oral Presentations - Preventing Type 1 Diabetes
Presenter:
Christoph Bausch, PhD, MBA, Chief Operating Officer, SAB BIO
Presentation Date and Time:
Friday, June 05, 2026, 2:45 - 3:00 PM CT
Location:
New Orleans Convention Center – Session Room 245 (Level 2)
Poster Presentation at FOCIS 2026 Annual Meeting:
Title
:
Positive Clinical Translation of a Juvenile NHP Study for Evaluating SAB-142, a Multi-Specific T-Cell Targeting T1D Therapy, in Humans
Session:
Exhibit and Poster Reception – Poster # W114
Presenter:
Diane Maher, PhD, Director, Program Management, SAB BIO
Presentation Date and Time:
Wednesday, June 10, 2026, 6:50 - 8:05 PM PT
Location:
San Francisco Marriott Marquis – Discovery Center Poster & Exhibit Hall – Salon 9
The presentations will be made available in the Presentations section of the Company’s website afterwards and will remain accessible following the conference.
About SAB-142
SAB-142 is a potentially disease-modifying, redosable immunotherapy in clinical development for the treatment of autoimmune type 1 diabetes (T1D). SAB-142 is a multi-specific, fully human anti-thymocyte globulin (hATG) with a mechanism of action analogous to that of rabbit ATG (rATG). rATG has demonstrated in multiple clinical trials the ability to slow disease progression in patients with new- or recent-onset of Stage 3 T1D. SAB-142, like rATG, directly targets multiple immune cells involved in destroying pancreatic beta cells, including modulation of “bad acting” T-lymphocytes. By stopping immune cells from attacking beta cells, this treatment has the potential to preserve insulin-producing beta cells.
About SAB BIO
SAB BIO is a clinical-stage biopharmaceutical company focused on developing multi-specific, high-potency, human immunoglobulin G (hIgG) to treat and prevent immune and autoimmune disorders. Using advanced genetic engineering and antibody science, SAB BIO developed a proprietary technology which holds the potential to generate additional novel therapeutic candidates utilizing the human immune response, without the need for human donors or convalescent plasma. SAB BIO has optimized genetic engineering in the development of transchromosomic cattle, or Tc-Bovine, to produce hIgG. SAB BIO’s drug development production system is able to generate a diverse repertoire of specifically targeted, high-potency, hIgGs that can address a wide range of serious unmet needs in human diseases. The Company’s lead candidate, SAB-142, targets autoimmune T1D with a disease-modifying therapeutic approach that aims to change the T1D treatment paradigm by delaying onset and potentially preventing disease progression of Stage 3 T1D patients. SAB-142 is currently being evaluated in newly diagnosed Stage 3 autoimmune T1D patients in a registrational Phase 2b clinical trial called SAFEGUARD. For more information, visit
www.sab.bio
.
Forward-Looking Statements
Certain statements made in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995. Forward-looking statements generally are accompanied by words such as “believe,” “may,” “will,” “to be,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook,” and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding future events, including statements about the development and clinical trial results of the Company’s T1D program and other discovery programs.
These statements are based on the current expectations of SAB BIO and are not predictions of actual performance, and are not intended to serve as, and must not be relied on, by any investor as a guarantee, prediction, definitive statement, or an assurance, of fact or probability. These statements are only current predictions or expectations, and are subject to known and unknown risks, uncertainties and other factors which may be beyond our control. Actual events and circumstances are difficult or impossible to predict, and these risks and uncertainties may cause our or our industry’s results, performance, or achievements to be materially different from those anticipated by these forward-looking statements. A further description of risks and uncertainties can be found in the sections captioned “Risk Factors” in our most recent annual report on Form 10-K, subsequent quarterly reports on Form 10-Q, as may be amended or supplemented from time to time, and other filings with or submissions to, the U.S. Securities and Exchange Commission, which are available at https://www.sec.gov/ . Except as otherwise required by law, SAB BIO disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events, or circumstances or otherwise.
CONTACTS
Investor Relations:
Christine Ryan
[email protected]
Media:
Sheila Carlson
[email protected]